Basic Information:

  VIRBase ID:  

VHID00114784

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H14-5p:  MIMAT0014691          TRIM8:  NM_030912     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H14-5p	TRIM8
miRBase Accession/Entrez ID	MIMAT0014691	81603
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	GERP//RNF27

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TRIM8	chr10:104414106(+) A-I      intronic chr10:104414115(+) A-I      intronic chr10:104414090(+) A-I      intronic chr10:104414073(+) A-I      intronic chr10:104412678(+) A-I      intronic chr10:104414083(+) A-I      intronic chr10:104413959(+) A-I      intronic chr10:104414016(+) A-I      intronic chr10:104412640(+) A-I      intronic chr10:104412795(+) A-I      intronic chr10:104412765(+) A-I      intronic chr10:104412700(+) A-I      intronic chr10:104414135(+) A-I      intronic chr10:104414098(+) A-I      intronic chr10:104414151(+) A-I      intronic chr10:104414047(+) A-I      intronic chr10:104414074(+) A-I      intronic chr10:104413967(+) A-I      intronic chr10:104413934(+) A-I      intronic chr10:104412617(+) A-I      intronic chr10:104414133(+) A-I      intronic chr10:104412690(+) A-I      intronic chr10:104412661(+) A-I      intronic chr10:104413982(+) A-I      intronic chr10:104414095(+) A-I      intronic chr10:104414096(+) A-I      intronic chr10:104412638(+) A-I      intronic chr10:104412790(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TRIM8	chr10:104414095(+) A-G intron -    22484847 chr10:104414133(+) A-G intron -    22484847 chr10:104414135(+) A-G intron -    22484847 chr10:104414151(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TRIM8	chr10:104404318-104404319(+) m6A 5'UTR       25456834//24981863//22575960//22608085 chr10:104404393-104404394(+) m6A CDS       24209618//25456834//24981863//22575960 chr10:104404466-104404467(+) m6A CDS       24209618//25456834//24981863 chr10:104404510-104404511(+) m6A CDS       24209618//25456834//24981863 chr10:104404576-104404577(+) m6A CDS       24981863//27773536 chr10:104404901-104404902(+) m6A CDS       24284625//24209618//25456834//24981863 chr10:104414431-104414432(+) m6A CDS//exon//intron       24209618//25456834//24981863 chr10:104414455-104414456(+) m6A CDS//exon//intron       24209618//25456834//24981863//22575960 chr10:104414464-104414465(+) m6A CDS//exon//intron       24209618//25456834//24981863//22575960 chr10:104414477-104414478(+) m6A CDS//exon//intron       24209618//25456834//24981863//22575960 chr10:104414488-104414489(+) m6A CDS//exon//intron       24209618//25456834//24981863//22575960 chr10:104414846-104414847(+) m6A CDS//exon       24209618//24981863//22575960 chr10:104414906-104414907(+) m6A CDS//exon       24209618//24981863//22575960 chr10:104414917-104414918(+) m6A CDS//exon       24284625//24209618//24981863//22575960 chr10:104414933-104414934(+) m6A CDS//exon       24284625//24209618//24981863//22575960 chr10:104416866-104416867(+) m6A CDS       24284625//24209618//25456834//24981863//22575960 chr10:104416940-104416941(+) m6A CDS       24284625//24209618//25456834//24981863//22575960 chr10:104417022-104417023(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr10:104417092-104417093(+) m6A CDS       24284625//24209618//24981863//22575960 chr10:104417183-104417184(+) m6A 3'UTR       24284625//24209618 chr10:104417747-104417748(+) m6A 3'UTR       24981863//27773535//22608085 chr10:104417752-104417753(+) m6A 3'UTR       24981863//27773535//22608085 chr10:104417781-104417782(+) m6A 3'UTR       24981863//27773535//22608085 chr10:104417866-104417867(+) m6A 3'UTR       24981863//27773535//22608085 chr10:104417981-104417982(+) m6A 3'UTR       24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TRIM8	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H14-5p
Interactor2: TRIM8

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg