Basic Information:

  VIRBase ID:  

VHID00113588

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H14-5p:  MIMAT0014691          HLA-E:  NM_005516     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H14-5p	HLA-E
miRBase Accession/Entrez ID	MIMAT0014691	3133
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HLA-6.2//QA1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	HLA-E	chr6:30459677(+) A-I      intronic chr6:30459838(+) A-I      intronic chr6:30459729(+) A-I      intronic chr6:30459726(+) A-I      intronic chr6:30459678(+) A-I      intronic chr6:30459654(+) A-I      intronic chr6:30459754(+) A-I      intronic chr6:30459731(+) A-I      intronic chr6:30459691(+) A-I      intronic chr6:30459854(+) A-I      intronic chr6:30459777(+) A-I      intronic chr6:30459789(+) A-I      intronic chr6:30459801(+) A-I      intronic chr6:30459700(+) A-I      intronic chr6:30459840(+) A-I      intronic chr6:30459643(+) A-I      intronic chr6:30459865(+) A-I      intronic chr6:30459739(+) A-I      intronic chr6:30459713(+) A-I      intronic chr6:30459817(+) A-I      intronic chr6:30459630(+) A-I      intronic chr6:30459667(+) A-I      intronic chr6:30459802(+) A-I      intronic chr6:30459760(+) A-I      intronic chr6:30459780(+) A-I      intronic chr6:30459592(+) A-I      intronic chr6:30459852(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	HLA-E	chr6:30458064(+) G-A exon CDS    21725310 chr6:30460176(+) A-C intron -    21725310 chr6:30461972(+) T-A intron -    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HLA-E	chr6:30457273-30457274(+) m6A 5'UTR       24981863 chr6:30457291-30457292(+) m6A 5'UTR//exon       24981863 chr6:30457320-30457321(+) m6A CDS//exon       24981863 chr6:30457362-30457363(+) m6A CDS//exon       24981863 chr6:30457443-30457444(+) m6A exon//intron       - chr6:30457682-30457683(+) m6A CDS//exon       24981863//26404942//27371828 chr6:30457690-30457691(+) m6A CDS//exon       24981863//26404942//27371828 chr6:30457706-30457707(+) m6A CDS//exon       24981863//26404942//27371828 chr6:30457994-30457995(+) m6A exon//intron       - chr6:30458086-30458087(+) m6A CDS//exon       26404942 chr6:30458130-30458131(+) m6A CDS//exon       26404942 chr6:30458144-30458145(+) m6A CDS//exon       26404942 chr6:30458154-30458155(+) m6A CDS//exon       26404942 chr6:30458229-30458230(+) m6A CDS//exon       26404942 chr6:30458924-30458925(+) m6A CDS//exon       24284625//26404942 chr6:30459413-30459414(+) Gm CDS       - chr6:30460869-30460870(+) m6A 3'UTR       24981863 chr6:30460892-30460893(+) m6A 3'UTR       24209618//24981863 chr6:30461100-30461101(+) m6A 3'UTR       24981863//26404942//22608085 chr6:30461144-30461145(+) m6A 3'UTR       26404942//22608085 chr6:30461329-30461330(+) m6A 3'UTR       26404942 chr6:30461443-30461444(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22608085 chr6:30461474-30461475(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22608085 chr6:30461634-30461635(+) m6A 3'UTR       25456834//22608085 chr6:30461651-30461652(+) m6A 3'UTR       25456834//22608085 chr6:30461659-30461660(+) m6A 3'UTR       25456834//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HLA-E	Chromatin K562 cells     - Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H14-5p
Interactor2: HLA-E

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg