Basic Information:

  VIRBase ID:  

VHID00104081

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H8-5p:  MIMAT0012597          APLP2:  NR_168391     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H8-5p	APLP2
miRBase Accession/Entrez ID	MIMAT0012597	334
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	APLP-2//APPH//APPL2//CDEBP

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	APLP2	chr11:129964176(+) A-I      intronic chr11:129944294(+) A-I      intronic chr11:129964209(+) A-I      intronic chr11:129964210(+) A-I      intronic chr11:129986589(+) A-I      intronic chr11:129986596(+) A-I      intronic chr11:129986601(+) A-I      intronic chr11:129955205(+) A-I      intronic chr11:129986610(+) A-I      intronic chr11:129964208(+) A-I      intronic chr11:129944172(+) A-I      intronic chr11:129944331(+) A-I      intronic chr11:129944332(+) A-I      intronic chr11:129975728(+) A-I      intronic chr11:129944333(+) A-I      intronic chr11:129944291(+) A-I      intronic chr11:129965146(+) A-I      intronic chr11:129965120(+) A-I      intronic chr11:129975253(+) A-I      intronic chr11:129950799(+) A-I      intronic chr11:129975832(+) A-I      intronic chr11:129986976(+) A-I      intronic chr11:129986896(+) A-I      intronic chr11:129975175(+) A-I      intronic chr11:129986629(+) A-I      intronic chr11:129976723(+) A-I      intronic chr11:129966515(+) A-I      intronic chr11:129944142(+) A-I      intronic chr11:129952979(+) A-I      intronic chr11:129944130(+) A-I      intronic chr11:129943526(+) A-I      intronic chr11:129943488(+) A-I      intronic chr11:129987851(+) A-I      intronic chr11:129986996(+) A-I      intronic chr11:129986824(+) A-I      intronic chr11:129987821(+) A-I      intronic chr11:129943629(+) A-I      intronic chr11:129976713(+) A-I      intronic chr11:129975778(+) A-I      intronic chr11:129974194(+) A-I      intronic chr11:129986595(+) A-I      intronic chr11:129953008(+) A-I      intronic chr11:129967334(+) A-I      intronic chr11:129975213(+) A-I      intronic chr11:129975099(+) A-I      intronic chr11:129943589(+) A-I      intronic chr11:129975256(+) A-I      intronic chr11:129975137(+) A-I      intronic chr11:129943684(+) A-I      intronic chr11:129975212(+) A-I      intronic chr11:129966431(+) A-I      intronic chr11:129975200(+) A-I      intronic chr11:129975716(+) A-I      intronic chr11:129975236(+) A-I      intronic chr11:129967340(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	APLP2	chr11:129939760-129939761(+) m6A 5'UTR//exon       25456834//24981863 chr11:129939779-129939780(+) m6A 5'UTR//exon       24284625//25456834//24981863 chr11:129939887-129939888(+) m6A CDS//exon       25456834//24981863//22575960 chr11:129979344-129979345(+) m6A 3'UTR//CDS//exon//intron       26404942 chr11:129979408-129979409(+) m6A 3'UTR//CDS//exon//intron       26404942//27773535 chr11:129979416-129979417(+) m6A 3'UTR//CDS//exon//intron       26404942//27773535 chr11:129979430-129979431(+) m6A 3'UTR//CDS//exon//intron       26404942//27773535 chr11:129979464-129979465(+) m6A 3'UTR//CDS//exon//intron       26404942//27773535 chr11:129991569-129991570(+) m6A 3'UTR//CDS//exon//intron       24981863//27773535//22575960 chr11:129991607-129991608(+) m6A 3'UTR//CDS//exon//intron       24981863//27773535//22575960 chr11:129991632-129991633(+) Am 3'UTR//CDS//exon//intron       - chr11:129991686-129991687(+) m6A 3'UTR//CDS//exon//intron       24981863//27773535//22575960 chr11:129992228-129992229(+) m6A 3'UTR//CDS//exon//intron       24981863//27773535 chr11:129992294-129992295(+) m6A 3'UTR//CDS//exon//intron       24981863//26404942//27773535 chr11:129992355-129992356(+) m6A 3'UTR//CDS//exon//intron       24981863//26404942//27773535 chr11:129992381-129992382(+) m6A 3'UTR//CDS//intron       24981863//26404942//27773535 chr11:129996641-129996642(+) m6A 3'UTR//CDS       27773535//22575960 chr11:129996648-129996649(+) Cm 3'UTR//CDS       - chr11:129996720-129996721(+) m6A 3'UTR//CDS       26404942//27773535//22575960 chr11:129997700-129997701(+) m6A 3'UTR//CDS       26404942//27773535//22575960 chr11:129997723-129997724(+) m6A 3'UTR//CDS       26404942//27773535//22575960 chr11:129999008-129999009(+) m6A 3'UTR//CDS       22575960 chr11:129999066-129999067(+) m6A 3'UTR//CDS       22575960 chr11:129999978-129999979(+) m6A 3'UTR//CDS       22575960 chr11:130003560-130003561(+) m6A 3'UTR//CDS       27773535 chr11:130005490-130005491(+) m6A 3'UTR//CDS       24981863//27773535 chr11:130005516-130005517(+) m6A 3'UTR//CDS       24981863//27773535//22575960 chr11:130005548-130005549(+) Gm 3'UTR//CDS       - chr11:130008680-130008681(+) m6A exon//intron       24981863//27773535//22575960 chr11:130008715-130008716(+) m6A exon//intron       24981863 chr11:130008723-130008724(+) m6A exon//intron       24981863 chr11:130010320-130010321(+) m6A 3'UTR//CDS//exon       24981863//27773535 chr11:130010373-130010374(+) m6A 3'UTR//CDS//exon       24981863//27773535 chr11:130010421-130010422(+) m6A exon//intron       24981863//27773535 chr11:130011841-130011842(+) Y 3'UTR//CDS//exon       26075521 chr11:130013278-130013279(+) m6A 3'UTR//CDS//exon       26404942//27773535//22575960 chr11:130013290-130013291(+) m6A 3'UTR//CDS//exon       26404942//27773535//22575960 chr11:130013305-130013306(+) m6A 3'UTR//CDS//exon       24981863//26404942//27773535//22575960 chr11:130013465-130013466(+) m6A 3'UTR//exon       24284625//25456834//24981863//26404942//27773535//22575960//22608085 chr11:130013473-130013474(+) m6A 3'UTR//exon       24284625//25456834//24981863//26404942//27773535//22608085 chr11:130013496-130013497(+) m6A 3'UTR//exon       24284625//25456834//24981863//26404942//27773535//22608085 chr11:130013558-130013559(+) m6A 3'UTR//exon       24284625//24981863//26404942//27773535//22608085 chr11:130013625-130013626(+) m6A 3'UTR//exon       27773535 chr11:130013852-130013853(+) m6A 3'UTR//exon       26404942 chr11:130013881-130013882(+) m6A 3'UTR//exon       26404942 chr11:130013905-130013906(+) m6A 3'UTR//exon       26404942 chr11:130014194-130014195(+) m6A 3'UTR       24284625//27773535 chr11:130014287-130014288(+) m6A 3'UTR       24284625//27773535 chr11:130014323-130014324(+) m6A 3'UTR       24284625 chr11:130014621-130014622(+) m6A 3'UTR       24981863//27773535 chr11:130014634-130014635(+) m6A 3'UTR       24981863//27773535 chr11:130014673-130014674(+) m6A 3'UTR       24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	APLP2	Chromatin HeLa-S3 cells|K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H8-5p
Interactor2: APLP2

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg