Basic Information:

  VIRBase ID:  

VHID00099373

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H6-3p:  MIMAT0008404          CHMP4B:  NM_176812     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H6-3p	CHMP4B
miRBase Accession/Entrez ID	MIMAT0008404	128866
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C20orf178//CHMP4A//CTPP3//CTRCT31//dJ553F4.4//Shax1//SNF7//SNF7-2//Vps32-2//VPS32B

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CHMP4B	chr20:32437708(+) A-I      intronic chr20:32410761(+) A-I      intronic chr20:32409892(+) A-I      intronic chr20:32409840(+) A-I      intronic chr20:32409456(+) A-I      intronic chr20:32409475(+) A-I      intronic chr20:32437353(+) A-I      intronic chr20:32437694(+) A-I      intronic chr20:32437716(+) A-I      intronic chr20:32437754(+) A-I      intronic chr20:32437766(+) A-I      intronic chr20:32406780(+) A-I      intronic chr20:32406790(+) A-I      intronic chr20:32437295(+) A-I      intronic chr20:32437285(+) A-I      intronic chr20:32411363(+) A-I      intronic chr20:32410874(+) A-I      intronic chr20:32410837(+) A-I      intronic chr20:32410801(+) A-I      intronic chr20:32410770(+) A-I      intronic chr20:32409122(+) A-I      intronic chr20:32407796(+) A-I      intronic chr20:32437721(+) A-I      intronic chr20:32424970(+) A-I      intronic chr20:32407696(+) A-I      intronic chr20:32437711(+) A-I      intronic chr20:32410700(+) A-I      intronic chr20:32406923(+) A-I      intronic chr20:32437291(+) A-I      intronic chr20:32409468(+) A-I      intronic chr20:32407718(+) A-I      intronic chr20:32407825(+) A-I      intronic chr20:32437230(+) A-I      intronic chr20:32409546(+) A-I      intronic chr20:32437147(+) A-I      intronic chr20:32437633(+) A-I      intronic chr20:32407850(+) A-I      intronic chr20:32437325(+) A-I      intronic chr20:32407863(+) A-I      intronic chr20:32409143(+) A-I      intronic chr20:32437651(+) A-I      intronic chr20:32406785(+) A-I      intronic chr20:32406918(+) A-I      intronic chr20:32409466(+) A-I      intronic chr20:32406908(+) A-I      intronic chr20:32437747(+) A-I      intronic chr20:32407719(+) A-I      intronic chr20:32437602(+) A-I      intronic chr20:32437804(+) A-I      intronic chr20:32437256(+) A-I      intronic chr20:32437682(+) A-I      intronic chr20:32406992(+) A-I      intronic chr20:32437399(+) A-I      intronic chr20:32424983(+) A-I      intronic chr20:32407816(+) A-I      intronic chr20:32406833(+) A-I      intronic chr20:32437229(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CHMP4B	chr20:32437651(+) A-I intron -    21960545 chr20:32407863(+) A-G intron -    22484847 chr20:32437633(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CHMP4B	chr20:32399184-32399185(+) m6A 5'UTR       24209618//25456834//24981863//27371828//27773536 chr20:32399365-32399366(+) m6A CDS       24209618//24981863//27773535//27371828//22575960 chr20:32399390-32399391(+) m6A CDS       24209618//24981863//27773535//27371828//22575960 chr20:32399455-32399456(+) m6A CDS       24209618//24981863//27773535//27371828//22575960 chr20:32436404-32436405(+) m6A CDS       24209618//22575960 chr20:32438759-32438760(+) m6A CDS       24209618//27773535 chr20:32438789-32438790(+) m6A CDS       24209618//27773535 chr20:32438808-32438809(+) m6A CDS       24209618//27773535 chr20:32438841-32438842(+) m6A CDS       24209618//27773535 chr20:32439908-32439909(+) m6A CDS       24209618//27773535 chr20:32439914-32439915(+) m6A CDS       24209618//27773535 chr20:32439923-32439924(+) m6A CDS       24209618//27773535 chr20:32439928-32439929(+) m6A CDS       24209618//27773535 chr20:32439953-32439954(+) m6A CDS       24209618//27773535 chr20:32439960-32439961(+) m6A CDS       24209618//24981863//27773535 chr20:32440004-32440005(+) m6A CDS       24209618//24981863//27773535 chr20:32441346-32441347(+) m6A CDS       24209618//24981863//27773535 chr20:32441392-32441393(+) m6A 3'UTR       24284625//24209618//24981863//22575960 chr20:32441396-32441397(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CHMP4B	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleoplasm K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H6-3p
Interactor2: CHMP4B

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg