Basic Information:

  VIRBase ID:  

VHID00097669

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H6-3p:  MIMAT0008404          SMYD5:  NM_006062     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H6-3p	SMYD5
miRBase Accession/Entrez ID	MIMAT0008404	10322
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	NN8-4AG//RAI15//RRG1//ZMYND23

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SMYD5	chr2:73443496(+) A-I      intronic chr2:73443450(+) A-I      intronic chr2:73443468(+) A-I      intronic chr2:73443920(+) A-I      intronic chr2:73444159(+) A-I      intronic chr2:73444216(+) A-I      intronic chr2:73444269(+) A-I      intronic chr2:73444280(+) A-I      intronic chr2:73443663(+) A-I      intronic chr2:73443639(+) A-I      intronic chr2:73443506(+) A-I      intronic chr2:73444289(+) A-I      intronic chr2:73443428(+) A-I      intronic chr2:73443966(+) A-I      intronic chr2:73444160(+) A-I      intronic chr2:73444219(+) A-I      intronic chr2:73444260(+) A-I      intronic chr2:73443735(+) A-I      intronic chr2:73443463(+) A-I      intronic chr2:73443678(+) A-I      intronic chr2:73443705(+) A-I      intronic chr2:73443758(+) A-I      intronic chr2:73443669(+) A-I      intronic chr2:73444340(+) A-I      intronic chr2:73443482(+) A-I      intronic chr2:73443564(+) A-I      intronic chr2:73443618(+) A-I      intronic chr2:73443641(+) A-I      intronic chr2:73443704(+) A-I      intronic chr2:73443473(+) A-I      intronic chr2:73443557(+) A-I      intronic chr2:73444355(+) A-I      intronic chr2:73443531(+) A-I      intronic chr2:73443635(+) A-I      intronic chr2:73443732(+) A-I      intronic chr2:73444209(+) A-I      intronic chr2:73443783(+) A-I      intronic chr2:73443980(+) A-I      intronic chr2:73444143(+) A-I      intronic chr2:73444128(+) A-I      intronic chr2:73443675(+) A-I      intronic chr2:73443959(+) A-I      intronic chr2:73443499(+) A-I      intronic chr2:73444263(+) A-I      intronic chr2:73444241(+) A-I      intronic chr2:73443793(+) A-I      intronic chr2:73443719(+) A-I      intronic chr2:73443755(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SMYD5	chr2:73443755(+) A-I intron -    22327324 chr2:73443497(+) A-G intron -    22484847 chr2:73443505(+) A-G intron -    22484847 chr2:73443507(+) A-G intron -    22484847 chr2:73443649(+) A-G intron -    22484847 chr2:73443654(+) A-G intron -    22484847 chr2:73443678(+) A-G intron -    22484847 chr2:73443704(+) A-G intron -    22484847 chr2:73443719(+) A-G intron -    22484847 chr2:73443755(+) A-G intron -    22484847 chr2:73443758(+) A-G intron -    22484847 chr2:73443908(+) A-G intron -    22484847 chr2:73443966(+) A-G intron -    22484847 chr2:73444128(+) A-G intron -    22484847 chr2:73444138(+) A-G intron -    22484847 chr2:73444143(+) A-G intron -    22484847 chr2:73444160(+) A-G intron -    22484847 chr2:73444197(+) A-G intron -    22484847 chr2:73444219(+) A-G intron -    22484847 chr2:73444282(+) A-G intron -    22484847 chr2:73444330(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SMYD5	chr2:73446067-73446068(+) Y CDS//exon       26075521 chr2:73452728-73452729(+) m6A exon//intron       - chr2:73452736-73452737(+) m6A exon//intron       - chr2:73452780-73452781(+) m6A CDS//exon       24284625//24209618//24981863 chr2:73452928-73452929(+) m6A CDS//exon       24284625//24209618//24981863 chr2:73452977-73452978(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr2:73453106-73453107(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr2:73453155-73453156(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:73453247-73453248(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr2:73453261-73453262(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr2:73453284-73453285(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr2:73453650-73453651(+) m6A 3'UTR       24284625 chr2:73453689-73453690(+) m6A 3'UTR       24284625 chr2:73453724-73453725(+) m6A 3'UTR       24284625 chr2:73453745-73453746(+) m6A 3'UTR       24284625 chr2:73453992-73453993(+) m6A 3'UTR       - chr2:73454015-73454016(+) m6A 3'UTR       - chr2:73454228-73454229(+) m6A 3'UTR       24284625 chr2:73454242-73454243(+) Y 3'UTR       26075521 chr2:73454246-73454247(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SMYD5	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H6-3p
Interactor2: SMYD5

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg