Detail Information

Basic Information:


  VIRBase ID:  

VHID00096272

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H6-3p:           DIRC1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsv1-miR-H6-3p DIRC1
miRBase
Accession/Entrez ID		 MIMAT0008404 116093
Organism Human alphaherpesvirus 1 (HSV-1) Homo sapiens
Category miRNA lncRNA
Alias - -

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DIRC1
chr2:189654751-189654752(-) m6A 5'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate DIRC1
Chromatin K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug DIRC1
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222
Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773
1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054
Tivozanib       9911830
Zibotentan       9910224
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786
PI-103       9884685
2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide       9874913
Osi-930       9868037
2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940
Tiotixene       941651
8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acid       92577
Benzethonium chloride       8478
Phenformin       8249
(E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717
2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide       71271629
N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473
(S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848
Belinostat       6918638
2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide       6918454
Temsirolimus       6918289
Daporinad       6914657
N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167
Melicopidine       68060
Dihydroartemisinyl ether, stereoisomer of NSC-685988       6712440
Hypopistephanine       6711179
AICA ribonucleotide       65110
Tanespimycin       6505803
Digitin       6474107
Ispinesib mesylate       6450816
Axitinib       6450551
Pelitinib       6445562
Dacinostat       6445533
Nilotinib       644241
4-(N-Hydroxyacetamido)stilbene       6433723
Verrucarin A, 3'-(acetyloxy)-7'-deoxo-2'-deoxy-4'-hydroxy-7'-(1-hydroxyethyl)-       5933240
Mitomycin       5746
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)       57339144
1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea       56962337
Gab-geldanamycin       5467747
Lfm-a13       54676905
Herveline O       5459269
Iridogermanal       5458843
Temozolomide       5394
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one       5382674
1-[2-[p-[alpha-(p-Methoxyphenyl)-beta-nitrostyryl]phenoxy]ethyl]pyrrolidine citrate (1:1)       5381092
Indanthren Corinth RK       5351878
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664
Bosutinib       5328940
Vorinostat       5311
5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione       5289247
Isotretinoin       5282379
2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one       5278396
8-Hydroxymanzamine A       5270765
Bis(2-hydroxy-1-naphthyl) disulfide       521106
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide       5113032
Tubastatin A       49850262
5-Tert-butyl-1H-pyrazole; trichlororuthenium       498460
Alectinib       49806720
Shikonin       479503
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one       4713
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432
(S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate       46907787
3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626
Avagacestat       46883536
2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine       46224516
N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454
(+)-Membrenone B       45028040
N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660
Tretinoin       444795
Dabrafenib       44462760
3-(2-(4-(4-(3-Fluorobenzyloxy)-3-chlorophenylamino)pyrimidin-5-yl)ethynyl)-N-methylbenzamide       44410704
6alpha-Senecioyloxychaparrinone       431194
Foretinib       42642645
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640
(2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol       42623900
Phosphine, 1,2-ethanediylbis[bis[2-(methylthio)phenyl]-       397601
Ptilomycalin A format salt       395755
2(3H)-Furanone, dihydro-3-(3,4,5-trimethoxybenzyl)-4-veratryl-, trans-       384878
1,4-Dimethoxy-7-bromo-5H-benzocycloheptene       384503
2,6-Dibromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol       3796
(1R)-3,3-Dibromocamphor       376765
2-[Bromo(iodo)methylidene]cyclohexan-1-one       376548
N-Hydroxy-N-methylpropanethioamide       371713
Etoposide       36462
3-Nitro-5-formylisoxazole       362479
5-Fluorouracil       3385
Buellolide       337850
(3-Phenoxypropyl)triphenylphosphonium bromide       3048782
Clomifene citrate       3033832
Elesclomol       300471
2-((2-Hydroxyethyl)thio)-3-methylnaphthalene-1,4-dione       2876
Tamoxifen       2733526
2-Hydroxy-4-((2,4,6-triamino-5-pyrimidinyl)diazenyl)phenylarsonic acid       272658
Gardenin A       261859
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965
2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557
4-[3-Fluoro-5-(4-morpholinyl)phenyl]-N-[4-[3-(4-morpholinyl)-1,2,4-triazol-1-yl]phenyl]-2-pyrimidinamine       25222038
Omipalisib       25167777
Ruxolitinib       25126798
Cabozantinib       25102847
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid       25022668
Navitoclax       24978538
MK-2206       24964624
Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314
Quizartinib       24889392
Ponatinib       24826799
Vismodegib       24776445
4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860
Cudc-101       24756910
N-(2-Iodylphenyl)-N-methylpivalamide       24205923
Diisopropoxybis(chinoline-8-olato)titanium(IV)       24202322
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide       24200489
Vincaleukoblastine       241903
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719
Bicalutamide       2375
Olaparib       23725625
7-Fluoro-3-trifluoromethyl-2-naftoylquioxaline 1,4-dioxide       23635287
(2E,5E)-2,5-Bis(thiophen-2-ylmethylene)cyclopentanone       2314623
Tenulin       227830
Lenalidomide       216326
Thalicarpine       21470
Enzastaurin       176167
Adiantifoline       167937
4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388
Gsk-690693       16725726
Fedratinib       16722836
Mercury, (acetyloxy)(pentamethylphenyl)-       16683786
Obatoclax mesylate       16681698
Docetaxel       148124
1-(Tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea       1401
(Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062
(E)-5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime       135421339
Pac-1       135421197
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one       135418940
Osi-027       135398516
Akt inhibitor VIII       135398501
N(4)-Octadecyl-1-arabinofuranosylcytosine       133043
Methotrexate       126941
Lestaurtinib       126565
Dactolisib       11977753
Veliparib       11960529
BAY 61-3606 dihydrochloride       11784504
N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511
4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372
4-[2-(2-Chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide       11634725
Idelalisib       11625818
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559
Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964
5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598
Linifanib       11485656
Bafetinib       11387605
N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846
4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide       11338033
8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430
Amuvatinib       11282283
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667
7-Ethyl-10-hydroxycamptothecin       104842
5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4h-Chromen-3-Yl 3,4-Di-O-Acetyl-6-Deoxy-alpha-L-Mannopyranoside       10459196
VX-702       10341154
N-(3-{[5-Iodo-4-({3-[(Thiophen-2-Ylcarbonyl)amino]propyl}amino)pyrimidin-2-Yl]amino}phenyl)pyrrolidine-1-Carboxamide       10077147
Masitinib       10074640
PDK1 inhibitor AR-12       10027278
1,4'-bipiperidine, 1'-decyl-, monohydrochloride       -
1-piperidinecarbodithioic acid, antimony complex       -
3-methoxy-estra-1,3,5(10)-triene-(17,16-c)pyrazole       -
4,7-[bis-n,n'-(3-amino-9-thioacetamido)-acridine]-biphenyl       -
4-morpholinecarbodithioic acid, antimony complex       -
5,6-ethylenediquino[3,2-b       -
5-methoxy, 4'-hydroxy,3-prenyl 7-o-rhamnopyranosido flavone       -
;9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluoroben...       -
benzo[1,2-b:4,5-b']-dithiophene-4,8-dione, 2,6-dinitro-       -
Cisplatin       -
[co(me2dtc)2(dee)]clo4       -
copper(ii) ocetanedioate 1,10-phenanthroline perchlorate       -
dalbergione       -
Denileukin Diftitox Ontak       -
Genentech Cpd 10       -
imidazole-5-one deri.       -
indoline, 5-chloro-1,3,3-trimethyl-2-methylene- (8ci)       -
JQ12       -
JW-7-24-1       -
KIN001-236       -
KIN001-244       -
KIN001-260       -
KIN001-266       -
KIN001-270       -
methylbenzethonium chloride (usan)       -
MPS-1-IN-1       -
;N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-[(4-chlorophenyl)...       -
N-methyl-N-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)-4-(2,6...       -
NPK76-II-72-1       -
Nutlin-3a (-)       -
ptmc       -
QL-X-138       -
QL-XI-92       -
QL-XII-47       -
SB52334       -
sodium[(tetratropolonato)bismuthate(iii)]       -
THZ-2-102-1       -
THZ-2-49       -
TL-1-85       -
TL-2-105       -
VNLG/124       -
WZ3105       -
XMD13-2       -
XMD14-99       -
XMD15-27       -

Interaction Network (The top 100 interactions):


Interactor1: hsv1-miR-H6-3p
Interactor2: DIRC1

Evidence Support:


Prediction-Evidence cRep//RNAHybrid
Support Database RepTar//VmiReg

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