Basic Information:

  VIRBase ID:  

VHID00095841

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H5-3p:  MIMAT0008403          FLCN:  NM_144997     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H5-3p	FLCN
miRBase Accession/Entrez ID	MIMAT0008403	201163
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BHD//DENND8B//FLCL

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FLCN	chr17:17115993(-) A-I      3'UTR chr17:17115981(-) A-I      3'UTR chr17:17115956(-) A-I      3'UTR chr17:17117433(-) A-I      intronic chr17:17115965(-) A-I      3'UTR chr17:17136722(-) A-I      intronic chr17:17138511(-) A-I      intronic chr17:17138472(-) A-I      intronic chr17:17137136(-) A-I      intronic chr17:17136804(-) A-I      intronic chr17:17136850(-) A-I      intronic chr17:17136991(-) A-I      intronic chr17:17137202(-) A-I      intronic chr17:17137704(-) A-I      intronic chr17:17138127(-) A-I      intronic chr17:17138181(-) A-I      intronic chr17:17138459(-) A-I      intronic chr17:17138314(-) A-I      intronic chr17:17115855(-) A-I      3'UTR chr17:17115896(-) A-I      3'UTR chr17:17115882(-) A-I      3'UTR chr17:17115873(-) A-I      3'UTR chr17:17116056(-) A-I      3'UTR chr17:17116087(-) A-I      3'UTR chr17:17115854(-) A-I      3'UTR chr17:17115842(-) A-I      3'UTR chr17:17115976(-) A-I      3'UTR chr17:17115864(-) A-I      3'UTR chr17:17116018(-) A-I      3'UTR chr17:17136967(-) A-I      intronic chr17:17138258(-) A-I      intronic chr17:17136791(-) A-I      intronic chr17:17136667(-) A-I      intronic chr17:17138482(-) A-I      intronic chr17:17137654(-) A-I      intronic chr17:17138035(-) A-I      intronic chr17:17136510(-) A-I      intronic chr17:17136801(-) A-I      intronic chr17:17115933(-) A-I      3'UTR chr17:17138681(-) A-I      intronic chr17:17115936(-) A-I      3'UTR chr17:17137802(-) A-I      intronic chr17:17115978(-) A-I      3'UTR chr17:17136962(-) A-I      intronic chr17:17115894(-) A-I      3'UTR chr17:17121837(-) A-I      intronic chr17:17137283(-) A-I      intronic chr17:17136866(-) A-I      intronic chr17:17137297(-) A-I      intronic chr17:17137801(-) A-I      intronic chr17:17115952(-) A-I      3'UTR chr17:17136747(-) A-I      intronic chr17:17137100(-) A-I      intronic chr17:17121827(-) A-I      intronic chr17:17136522(-) A-I      intronic chr17:17125568(-) A-I      intronic chr17:17137992(-) A-I      intronic chr17:17115840(-) A-I      3'UTR chr17:17137326(-) A-I      intronic chr17:17137240(-) A-I      intronic chr17:17137729(-) A-I      intronic chr17:17116053(-) A-I      3'UTR chr17:17138169(-) A-I      intronic chr17:17137663(-) A-I      intronic chr17:17117439(-) A-I      intronic chr17:17137970(-) A-I      intronic chr17:17117366(-) A-I      intronic chr17:17137978(-) A-I      intronic chr17:17138755(-) A-I      intronic chr17:17123528(-) A-I      ncRNA chr17:17136410(-) A-I      intronic chr17:17123143(-) A-I      ncRNA chr17:17138653(-) A-I      intronic chr17:17136963(-) A-I      intronic chr17:17138542(-) A-I      intronic chr17:17137434(-) A-I      intronic chr17:17137622(-) A-I      intronic chr17:17137995(-) A-I      intronic chr17:17116850(-) A-I      3'UTR chr17:17115988(-) A-I      3'UTR chr17:17116845(-) A-I      3'UTR chr17:17116844(-) A-I      3'UTR chr17:17116838(-) A-I      3'UTR chr17:17116854(-) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FLCN	chr17:17116845(-) A-I exon 3'UTR    22327324 chr17:17128025(-) A-I intron -    22327324 chr17:17128025(-) A-G intron -    21725310   //22484847 chr17:17127961(-) A-G intron -    22484847 chr17:17128018(-) A-G intron -    22484847 chr17:17128022(-) A-G intron -    22484847 chr17:17138755(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FLCN	chr17:17116132-17116133(-) m6A 3'UTR       27773535 chr17:17116290-17116291(-) m6A 3'UTR       27773535 chr17:17116446-17116447(-) m6A 3'UTR       24209618//25456834//24981863//27773535//22575960//22608085 chr17:17116636-17116637(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr17:17116649-17116650(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr17:17116656-17116657(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr17:17116662-17116663(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr17:17116689-17116690(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr17:17116714-17116715(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr17:17116790-17116791(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr17:17116843-17116844(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr17:17116900-17116901(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085 chr17:17116943-17116944(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr17:17116972-17116973(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr17:17117030-17117031(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr17:17117074-17117075(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr17:17117116-17117117(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr17:17117134-17117135(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr17:17118334-17118335(-) m6A CDS       27773535 chr17:17118355-17118356(-) m6A CDS       27773535 chr17:17120443-17120444(-) m6A CDS//exon       27371828 chr17:17122495-17122496(-) m6A CDS       27371828 chr17:17122910-17122911(-) m6A exon//intron       27371828 chr17:17123219-17123220(-) m6A exon//intron       27773535 chr17:17129581-17129582(-) m6A CDS//exon       - chr17:17131212-17131213(-) m6A CDS//exon       24981863 chr17:17131287-17131288(-) m6A CDS//exon       24981863//27371828 chr17:17131341-17131342(-) m6A CDS//exon//intron       24284625//27773535//27371828 chr17:17132080-17132081(-) m6A exon//intron       27773535 chr17:17132098-17132099(-) m6A exon//intron       27773535 chr17:17132105-17132106(-) m6A exon//intron       27773535 chr17:17132217-17132218(-) m6A exon//intron       27773535 chr17:17135158-17135159(-) m6A 5'UTR//exon//intron       27773535 chr17:17140274-17140275(-) m6A 5'UTR//exon       27371828//27773536 chr17:17140286-17140287(-) m6A 5'UTR//exon       27371828//27773536 chr17:17140414-17140415(-) m6A 5'UTR//exon       27371828//27773536 chr17:17140467-17140468(-) m6A 5'UTR//exon       27371828//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	FLCN	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H5-3p
Interactor2: FLCN

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg