Basic Information:

  VIRBase ID:  

VHID00091284

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H4-3p:  MIMAT0008402          SIKE1:  NR_049742     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H4-3p	SIKE1
miRBase Accession/Entrez ID	MIMAT0008402	80143
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	SIKE

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SIKE1	chr1:115312883(-) A-I      3'UTR chr1:115312910(-) A-I      3'UTR chr1:115312918(-) A-I      3'UTR chr1:115312870(-) A-I      3'UTR chr1:115316790(-) A-I      3'UTR chr1:115318264(-) A-I      intronic chr1:115321596(-) A-I      ncRNA chr1:115312893(-) A-I      3'UTR chr1:115318224(-) A-I      intronic chr1:115321595(-) A-I      ncRNA chr1:115318354(-) A-I      intronic chr1:115318331(-) A-I      intronic chr1:115318212(-) A-I      intronic chr1:115312977(-) A-I      3'UTR chr1:115318347(-) A-I      intronic chr1:115318291(-) A-I      intronic chr1:115318294(-) A-I      intronic chr1:115312935(-) A-I      3'UTR chr1:115318230(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SIKE1	chr1:115312893(-) A-G exon 3'UTR    22484847 chr1:115318279(-) T-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SIKE1	chr1:115312291-115312292(-) m6A 3'UTR       27773535 chr1:115312544-115312545(-) m6A 3'UTR       27773535 chr1:115312592-115312593(-) m6A 3'UTR       27773535 chr1:115312625-115312626(-) m6A 3'UTR       27773535 chr1:115312632-115312633(-) m6A 3'UTR       27773535 chr1:115312652-115312653(-) m6A 3'UTR       27773535 chr1:115314291-115314292(-) m6A 3'UTR       27773535 chr1:115314298-115314299(-) m6A 3'UTR       27773535 chr1:115314369-115314370(-) m6A 3'UTR       27773535 chr1:115316627-115316628(-) m6A 3'UTR       27773535 chr1:115316643-115316644(-) m6A 3'UTR       27773535 chr1:115316668-115316669(-) m6A 3'UTR       27773535 chr1:115316886-115316887(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr1:115316916-115316917(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr1:115316925-115316926(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr1:115316978-115316979(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr1:115321558-115321559(-) m6A exon//intron       24209618//27773535 chr1:115321850-115321851(-) Am CDS//exon       - chr1:115322735-115322736(-) m6A CDS//exon//intron       24209618 chr1:115322750-115322751(-) m6A CDS//exon//intron       24209618 chr1:115322765-115322766(-) m6A CDS//exon//intron       24209618 chr1:115322791-115322792(-) m6A CDS//exon//intron       24209618 chr1:115322807-115322808(-) m6A CDS//exon//intron       24209618//27773536 chr1:115322951-115322952(-) m6A exon//intron       27371828 chr1:115323073-115323074(-) m6A CDS//exon       27371828//27773536 chr1:115323086-115323087(-) m6A CDS//exon       27371828//27773536 chr1:115323296-115323297(-) m6A 5'UTR//exon       24981863//27371828//27773536//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SIKE1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H4-3p
Interactor2: SIKE1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg