Basic Information:

  VIRBase ID:  

VHID00088924

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H4-5p:  MIMAT0008401          UNC5B:  NM_001244889     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H4-5p	UNC5B
miRBase Accession/Entrez ID	MIMAT0008401	219699
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	p53RDL1//UNC5H2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	UNC5B	chr10:73032703(+) A-I      intronic chr10:73033865(+) A-I      intronic chr10:73033864(+) A-I      intronic chr10:73036271(+) A-I      intronic chr10:73057335(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	UNC5B	chr10:72972409-72972410(+) m6A 5'UTR       24209618 chr10:72972494-72972495(+) m6A 5'UTR       24209618 chr10:72972686-72972687(+) m6A 5'UTR       24209618//27773536 chr10:72972701-72972702(+) m6A 5'UTR       24209618//27773536 chr10:72972726-72972727(+) m6A 5'UTR       24209618//27773536 chr10:72972800-72972801(+) m6A CDS       24209618 chr10:73051255-73051256(+) m6A CDS       24981863 chr10:73051275-73051276(+) m6A CDS       24981863 chr10:73057843-73057844(+) m6A CDS       25456834 chr10:73058918-73058919(+) m6A CDS       24209618//25456834//24981863//22608085 chr10:73058951-73058952(+) m6A CDS       24209618//25456834//24981863//22575960//22608085 chr10:73059026-73059027(+) m6A CDS       24209618//25456834//24981863//22575960//22608085 chr10:73059044-73059045(+) m6A 3'UTR       24209618//25456834//24981863//22608085 chr10:73059061-73059062(+) m6A 3'UTR       24209618//25456834//24981863//22608085 chr10:73059181-73059182(+) m6A 3'UTR       24209618//25456834 chr10:73059502-73059503(+) m6A 3'UTR       24981863 chr10:73059560-73059561(+) m6A 3'UTR       24981863 chr10:73059590-73059591(+) m6A 3'UTR       24981863 chr10:73059598-73059599(+) m6A 3'UTR       24981863 chr10:73059617-73059618(+) m6A 3'UTR       24981863 chr10:73062054-73062055(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	UNC5B	Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsv1-miR-H4-5p	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H4-5p
Interactor2: UNC5B

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg