Basic Information:

  VIRBase ID:  

VHID00088754

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H4-5p:  MIMAT0008401          UHMK1:  NM_144624     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H4-5p	UHMK1
miRBase Accession/Entrez ID	MIMAT0008401	127933
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	KIS//KIST//P-CIP2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	UHMK1	chr1:162471160(+) A-I      intronic chr1:162482992(+) A-I      intronic chr1:162486903(+) A-I      intronic chr1:162486968(+) A-I      intronic chr1:162486913(+) A-I      intronic chr1:162471101(+) A-I      intronic chr1:162482871(+) A-I      intronic chr1:162482928(+) A-I      intronic chr1:162482982(+) A-I      intronic chr1:162476963(+) A-I      intronic chr1:162476534(+) A-I      intronic chr1:162488700(+) A-I      intronic chr1:162489710(+) A-I      intronic chr1:162477937(+) A-I      intronic chr1:162489720(+) A-I      intronic chr1:162476488(+) A-I      intronic chr1:162489775(+) A-I      intronic chr1:162489892(+) A-I      intronic chr1:162489782(+) A-I      intronic chr1:162471687(+) A-I      intronic chr1:162471046(+) A-I      intronic chr1:162471023(+) A-I      intronic chr1:162486817(+) A-I      intronic chr1:162473333(+) A-I      intronic chr1:162491488(+) A-I      intronic chr1:162477558(+) A-I      intronic chr1:162489918(+) A-I      intronic chr1:162477489(+) A-I      intronic chr1:162491519(+) A-I      intronic chr1:162477567(+) A-I      intronic chr1:162473286(+) A-I      intronic chr1:162477049(+) A-I      intronic chr1:162476990(+) A-I      intronic chr1:162477929(+) A-I      intronic chr1:162473191(+) A-I      intronic chr1:162489806(+) A-I      intronic chr1:162487528(+) A-I      intronic chr1:162487070(+) A-I      intronic chr1:162473280(+) A-I      intronic chr1:162473238(+) A-I      intronic chr1:162488316(+) A-I      intronic chr1:162489712(+) A-I      intronic chr1:162489788(+) A-I      intronic chr1:162489869(+) A-I      intronic chr1:162477931(+) A-I      intronic chr1:162478645(+) A-I      intronic chr1:162478269(+) A-I      intronic chr1:162481146(+) A-I      intronic chr1:162488351(+) A-I      intronic chr1:162482857(+) A-I      intronic chr1:162489758(+) A-I      intronic chr1:162478371(+) A-I      intronic chr1:162478261(+) A-I      intronic chr1:162483004(+) A-I      intronic chr1:162489001(+) A-I      intronic chr1:162476532(+) A-I      intronic chr1:162476466(+) A-I      intronic chr1:162482812(+) A-I      intronic chr1:162488987(+) A-I      intronic chr1:162483956(+) A-I      intronic chr1:162489831(+) A-I      intronic chr1:162478124(+) A-I      intronic chr1:162471024(+) A-I      intronic chr1:162476604(+) A-I      intronic chr1:162487075(+) A-I      intronic chr1:162486929(+) A-I      intronic chr1:162478479(+) A-I      intronic chr1:162473278(+) A-I      intronic chr1:162482849(+) A-I      intronic chr1:162489825(+) A-I      intronic chr1:162478232(+) A-I      intronic chr1:162482977(+) A-I      intronic chr1:162478041(+) A-I      intronic chr1:162473142(+) A-I      intronic chr1:162482773(+) A-I      intronic chr1:162477930(+) A-I      intronic chr1:162485639(+) A-I      intronic chr1:162476467(+) A-I      intronic chr1:162488985(+) A-I      intronic chr1:162473218(+) A-I      intronic chr1:162487030(+) A-I      intronic chr1:162491334(+) A-I      intronic chr1:162473144(+) A-I      intronic chr1:162486966(+) A-I      intronic chr1:162477583(+) A-I      intronic chr1:162486942(+) A-I      intronic chr1:162489815(+) A-I      intronic chr1:162491322(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	UHMK1	chr1:162471024(+) A-G intron -    22484847 chr1:162473278(+) A-G intron -    22484847 chr1:162476466(+) A-G intron -    22484847 chr1:162476467(+) A-G intron -    22484847 chr1:162476532(+) A-G intron -    22484847 chr1:162477583(+) A-G intron -    22484847 chr1:162477930(+) A-G intron -    22484847 chr1:162477931(+) A-G intron -    22484847 chr1:162481146(+) A-G intron -    22484847 chr1:162481147(+) G-A intron -    22484847 chr1:162482773(+) A-G intron -    22484847 chr1:162482849(+) A-G intron -    22484847 chr1:162482857(+) A-G intron -    22484847 chr1:162483004(+) A-G intron -    22484847 chr1:162485639(+) A-G intron -    22484847 chr1:162486966(+) A-G intron -    22484847 chr1:162487030(+) A-G intron -    22484847 chr1:162487075(+) A-G intron -    22484847 chr1:162488351(+) A-G intron -    22484847 chr1:162489712(+) A-G intron -    22484847 chr1:162489788(+) A-G intron -    22484847 chr1:162489831(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	UHMK1	chr1:162469955-162469956(+) m6A CDS//exon       - chr1:162469997-162469998(+) m6A CDS//exon       - chr1:162470012-162470013(+) m6A CDS//exon       - chr1:162487931-162487932(+) m6A CDS//exon//intron       22575960 chr1:162487976-162487977(+) m6A CDS//exon//intron       22575960 chr1:162492328-162492329(+) m6A 3'UTR//CDS//exon       24284625//24981863 chr1:162492354-162492355(+) m6A 3'UTR//exon       24284625//24981863 chr1:162492410-162492411(+) m6A 3'UTR//exon       24284625//24981863 chr1:162493551-162493552(+) m6A 3'UTR//exon       24981863 chr1:162493635-162493636(+) Tm 3'UTR//exon       - chr1:162493650-162493651(+) m6A 3'UTR//exon       24981863 chr1:162495183-162495184(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	UHMK1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsv1-miR-H4-5p	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H4-5p
Interactor2: UHMK1

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg