Basic Information:

  VIRBase ID:  

VHID00088666

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H4-5p:  MIMAT0008401          FBXO44:  NM_183412     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H4-5p	FBXO44
miRBase Accession/Entrez ID	MIMAT0008401	93611
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	FBG3//FBX30//Fbx44//FBX6A//Fbxo6a

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FBXO44	chr1:11719289(+) A-I      intronic chr1:11719268(+) A-I      intronic chr1:11719258(+) A-I      intronic chr1:11719249(+) A-I      intronic chr1:11719293(+) A-I      intronic chr1:11719259(+) A-I      intronic chr1:11719294(+) A-I      intronic chr1:11719287(+) A-I      intronic chr1:11721078(+) A-I      intronic chr1:11717677(+) A-I      intronic chr1:11720318(+) A-I      intronic chr1:11721017(+) A-I      intronic chr1:11721076(+) A-I      intronic chr1:11717678(+) A-I      intronic chr1:11719385(+) A-I      intronic chr1:11719414(+) A-I      intronic chr1:11716494(+) A-I      intronic chr1:11717525(+) A-I      intronic chr1:11720426(+) A-I      intronic chr1:11717535(+) A-I      intronic chr1:11720497(+) A-I      intronic chr1:11717541(+) A-I      intronic chr1:11716432(+) A-I      intronic chr1:11721048(+) A-I      intronic chr1:11721105(+) A-I      intronic chr1:11719286(+) A-I      intronic chr1:11719324(+) A-I      intronic chr1:11719815(+) A-I      intronic chr1:11719173(+) A-I      intronic chr1:11719736(+) A-I      intronic chr1:11720320(+) A-I      intronic chr1:11719285(+) A-I      intronic chr1:11719437(+) A-I      intronic chr1:11720479(+) A-I      intronic chr1:11720289(+) A-I      intronic chr1:11719183(+) A-I      intronic chr1:11719360(+) A-I      intronic chr1:11719269(+) A-I      intronic chr1:11720391(+) A-I      intronic chr1:11719292(+) A-I      intronic chr1:11720912(+) A-I      intronic chr1:11719814(+) A-I      intronic chr1:11719646(+) A-I      intronic chr1:11719284(+) A-I      intronic chr1:11719313(+) A-I      intronic chr1:11720319(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FBXO44	chr1:11716432(+) A-G intron -    22484847 chr1:11719284(+) A-G intron -    22484847 chr1:11719285(+) A-G intron -    22484847 chr1:11719286(+) A-G intron -    22484847 chr1:11720289(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FBXO44	chr1:11714619-11714620(+) m6A 5'UTR       25456834//24981863//27773536 chr1:11715435-11715436(+) m6A 5'UTR//intron       24981863 chr1:11715562-11715563(+) m6A 5'UTR//intron       24284625//24981863 chr1:11718871-11718872(+) m6A CDS       24284625 chr1:11718884-11718885(+) m6A CDS       24284625 chr1:11721253-11721254(+) m6A CDS       24284625 chr1:11721355-11721356(+) m6A 3'UTR//CDS       - chr1:11721369-11721370(+) m6A 3'UTR//intron       - chr1:11721430-11721431(+) m6A 3'UTR//intron       - chr1:11721678-11721679(+) m6A 3'UTR//intron       - chr1:11721715-11721716(+) m6A 3'UTR//intron       - chr1:11721724-11721725(+) m6A 3'UTR//intron       - chr1:11721909-11721910(+) m6A 3'UTR//intron       25456834//24981863 chr1:11721919-11721920(+) m6A 3'UTR//intron       25456834//24981863 chr1:11721957-11721958(+) m6A 3'UTR//intron       25456834//24981863 chr1:11722024-11722025(+) m6A 3'UTR//intron       24284625//25456834 chr1:11722077-11722078(+) m6A 3'UTR//intron       24284625//25456834 chr1:11722095-11722096(+) m6A 3'UTR//intron       24284625//25456834 chr1:11722214-11722215(+) m6A 3'UTR//intron       24284625//25456834 chr1:11722229-11722230(+) m6A 3'UTR//intron       24284625//25456834 chr1:11722259-11722260(+) m6A 3'UTR//intron       24284625//25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	FBXO44	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol K562 cells     - Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsv1-miR-H4-5p	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H4-5p
Interactor2: FBXO44

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg