Basic Information:

  VIRBase ID:  

VHID00088530

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H4-5p:  MIMAT0008401          VANGL1:  NM_138959     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H4-5p	VANGL1
miRBase Accession/Entrez ID	MIMAT0008401	81839
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	KITENIN//LPP2//STB2//STBM2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	VANGL1	chr1:116238436(+) A-I      3'UTR chr1:116224285(+) A-I      intronic chr1:116231597(+) A-I      intronic chr1:116224275(+) A-I      intronic chr1:116231634(+) A-I      intronic chr1:116231619(+) A-I      intronic chr1:116216495(+) A-I      intronic chr1:116230490(+) A-I      intronic chr1:116230432(+) A-I      intronic chr1:116229327(+) A-I      intronic chr1:116197088(+) A-I      intronic chr1:116230515(+) A-I      intronic chr1:116204507(+) A-I      intronic chr1:116229325(+) A-I      intronic chr1:116237239(+) A-I      3'UTR chr1:116217907(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	VANGL1	chr1:116237239(+) A-I intron -    21960545

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	VANGL1	chr1:116184671-116184672(+) m6A 5'UTR       24981863 chr1:116194099-116194100(+) m6A CDS       24981863 chr1:116202268-116202269(+) m6A CDS       24284625//24981863 chr1:116202279-116202280(+) m6A CDS       24284625//24981863 chr1:116202379-116202380(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr1:116206299-116206300(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:116206348-116206349(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:116206369-116206370(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:116206378-116206379(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:116206436-116206437(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr1:116206553-116206554(+) m6A CDS       24284625//24209618//24981863//22608085 chr1:116206575-116206576(+) m6A CDS       24284625//24209618//24981863//22608085 chr1:116206705-116206706(+) m6A CDS       24284625//24209618 chr1:116206714-116206715(+) m6A CDS       24284625//24209618 chr1:116225030-116225031(+) Y CDS//exon       26075521 chr1:116227999-116228000(+) m6A CDS       24284625//24209618 chr1:116228080-116228081(+) m6A CDS       24284625//24209618//24981863//22608085 chr1:116233791-116233792(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:116233884-116233885(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:116233947-116233948(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr1:116233988-116233989(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr1:116234110-116234111(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr1:116234223-116234224(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:116234267-116234268(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:116234370-116234371(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085 chr1:116234381-116234382(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085 chr1:116234406-116234407(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:116234615-116234616(+) m6A 3'UTR       24284625 chr1:116235034-116235035(+) m6A 3'UTR       24284625 chr1:116235039-116235040(+) m6A 3'UTR       24284625 chr1:116235130-116235131(+) m6A 3'UTR       24284625 chr1:116235195-116235196(+) m6A 3'UTR       24284625//24981863 chr1:116235273-116235274(+) m6A 3'UTR       24284625//24981863 chr1:116235318-116235319(+) m6A 3'UTR       25456834 chr1:116235397-116235398(+) m6A 3'UTR       25456834 chr1:116235451-116235452(+) m6A 3'UTR       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	VANGL1	Chromatin K562 cells     - Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsv1-miR-H4-5p	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H4-5p
Interactor2: VANGL1

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg