Basic Information:

  VIRBase ID:  

VHID00088527

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H4-5p:  MIMAT0008401          ITM2C:  NM_001012514     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H4-5p	ITM2C
miRBase Accession/Entrez ID	MIMAT0008401	81618
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BRI3//BRICD2C//E25//E25C//ITM3

RNA Editing:

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ITM2C	chr2:231732383(+) A-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ITM2C	chr2:231729482-231729483(+) m6A 5'UTR       25456834//24981863 chr2:231729647-231729648(+) m6A 5'UTR//intron       25456834//24981863 chr2:231729687-231729688(+) m6A 5'UTR//intron       24284625//25456834//24981863 chr2:231742229-231742230(+) m6A CDS       24284625 chr2:231742746-231742747(+) m6A CDS       24284625 chr2:231742773-231742774(+) m6A CDS       24284625 chr2:231742831-231742832(+) m6A 3'UTR       24284625 chr2:231743130-231743131(+) m6A 3'UTR//CDS       24209618//24981863 chr2:231743284-231743285(+) m6A 3'UTR//CDS       24209618 chr2:231743328-231743329(+) m6A 3'UTR//CDS       24209618 chr2:231743375-231743376(+) m6A 3'UTR//CDS       24209618 chr2:231743464-231743465(+) m6A 3'UTR       24209618 chr2:231743486-231743487(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ITM2C	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsv1-miR-H4-5p	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H4-5p
Interactor2: ITM2C

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg