Detail Information

Basic Information:


  VIRBase ID:  

VHID00086790

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H4-5p:           C8orf86:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsv1-miR-H4-5p C8orf86
miRBase
Accession/Entrez ID		 MIMAT0008401 389649
Organism Human alphaherpesvirus 1 (HSV-1) Homo sapiens
Category miRNA lncRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR C8orf86
chr8:38380616(-) A-I      intronic
chr8:38376102(-) A-I      intronic
chr8:38379946(-) A-I      intronic
chr8:38380546(-) A-I      intronic
chr8:38369094(-) A-I      3'UTR
chr8:38381887(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase C8orf86
chr8:38385959-38385960(-) m6A CDS       25456834
chr8:38385966-38385967(-) m6A CDS       25456834
chr8:38385974-38385975(-) m6A CDS       25456834
chr8:38386004-38386005(-) m6A CDS       25456834
chr8:38386020-38386021(-) m6A CDS       25456834
chr8:38386026-38386027(-) m6A CDS       25456834
chr8:38386075-38386076(-) m6A CDS       25456834

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hsv1-miR-H4-5p
Topotecan       60700
C8orf86
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222
6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile       9956119
Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773
5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride       9938202
1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054
Tivozanib       9911830
Zibotentan       9910224
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786
PI-103       9884685
2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide       9874913
Osi-930       9868037
2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528
8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acid       92577
Phenformin       8249
Acetic acid, [(aminoiminomethyl)thio]-       81899
(E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717
Nonactin       72519
2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide       71271629
N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473
(S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848
Belinostat       6918638
2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide       6918454
Daporinad       6914657
N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167
17-Hydroxyjolkinolide B       6712607
AICA ribonucleotide       65110
Tanespimycin       6505803
1-Phenyl-3-[(3-phenylimidazolidin-1-yl)methyl]imidazolidine       6482345
Ispinesib mesylate       6450816
Axitinib       6450551
Pelitinib       6445562
Dacinostat       6445533
Nilotinib       644241
Gemcitabine       60750
Mitomycin       5746
Methyl N-[6-[3-[[2-fluoro-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1H-benzimidazol-2-yl]carbamate;hydrochloride       57399798
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)       57339144
1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea       56962337
2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid       54685215
Mito-tempol       54613387
2-Methylthiazolidine-2,4-dicarbonylic acid-di-sodium salt       54612624
Curromycin A.B mixture       54608021
Iridogermanal       5458843
Cristatic acid       5458761
Temozolomide       5394
Senecionine N-oxide       5380876
Bleomycin a2       5360373
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664
Bosutinib       5328940
Vorinostat       5311
Imatinib       5291
5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione       5289247
Isotretinoin       5282379
2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one       5278396
Bis(2-hydroxy-1-naphthyl) disulfide       521106
2-{[4-(5-Ethylpyrimidin-4-Yl)piperazin-1-Yl]methyl}-5-(Trifluoromethyl)-1h-Benzimidazole       51371303
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide       5113032
Tubastatin A       49850262
Alectinib       49806720
Probucol       4912
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432
(S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate       46907787
3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626
Avagacestat       46883536
2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine       46224516
N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454
N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660
Tretinoin       444795
Refametinib       44182295
Pyrodelphinine       431677
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640
(2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol       42623900
5-Fluoro-2-(3-Ethoxy-4-hydroxyphenyl)benzothiazole       404994
Methyl 5-[2-(2,5-dimethoxyphenyl)ethynyl]-2-methoxybenzoate       403337
23-O-Acetylshengmanol xyloside       399180
Ethyl-diphenyl-(2-phenylethynyl)phosphanium;iodide       386463
Etoposide       36462
Nilacrone       364456
1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)-       362170
5-Fluorouracil       3385
Methyl ciliarate       338441
Ehretinine       336435
2-Methyl-2-[4-(Naphthalen-1-Yl)phenoxy]propanoic Acid       327338
Doxorubicin       31703
Cetalkonium chloride       31202
Elesclomol       300471
Tamoxifen       2733526
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965
2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557
Omipalisib       25167777
Ruxolitinib       25126798
Cabozantinib       25102847
Navitoclax       24978538
MK-2206       24964624
Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314
1-Methyl-3-octadecylimidazolium hexafluorophosphate       24944555
Quizartinib       24889392
Ponatinib       24826799
Vismodegib       24776445
4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860
Cudc-101       24756910
Vincaleukoblastine       241903
Menisperine iodide       24189461
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719
Bicalutamide       2375
Tricinolone acetophenonide       235856
(2E,5E)-2,5-Bis(thiophen-2-ylmethylene)cyclopentanone       2314623
Tenulin       227830
Nutlin-3       216345
Lenalidomide       216326
Enzastaurin       176167
4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388
Gsk-690693       16725726
Fedratinib       16722836
N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin-4-yl)ethoxy]benzamide       16095342
Irofulven       148189
Docetaxel       148124
1-(Tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea       1401
Astrazon Orange R       135747272
(Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062
Talazoparib       135565082
(E)-5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime       135421339
Pac-1       135421197
Osi-027       135398516
Dovitinib       135398510
Akt inhibitor VIII       135398501
Methotrexate       126941
Lestaurtinib       126565
Veliparib       11960529
BAY 61-3606 dihydrochloride       11784504
N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511
Trametinib       11707110
4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372
4-[2-(2-Chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide       11634725
Crizotinib       11626560
Idelalisib       11625818
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559
Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964
5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598
Linifanib       11485656
1-Decyl-3-methylimidazolium tetrafluoroborate       11461044
Bafetinib       11387605
N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846
4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide       11338033
8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430
Amuvatinib       11282283
3-(4-Amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c]pyridin-7-yl)benzenesulfonamide       11281930
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667
7-Ethyl-10-hydroxycamptothecin       104842
5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4h-Chromen-3-Yl 3,4-Di-O-Acetyl-6-Deoxy-alpha-L-Mannopyranoside       10459196
VX-702       10341154
Masitinib       10074640
PDK1 inhibitor AR-12       10027278
1,1'-(benzo[d][1,3]dioxol-5-ylmethylene)dipiperazine       -
1,4-benzenediamine (9ci), n-butyl-n'-phenyl-       -
benzamide, n-(2,3-dimethylphenyl)-2-hydroxy-3-nitro- (9ci)       -
benzo[1,2-b:4,5-b']-dithiophene-4,8-dione, 2,6-dinitro-       -
Bleomycin (50 uM)       -
Genentech Cpd 10       -
JQ12       -
JW-7-24-1       -
KIN001-236       -
KIN001-244       -
KIN001-260       -
KIN001-266       -
KIN001-270       -
MPS-1-IN-1       -
NPK76-II-72-1       -
Nutlin-3a (-)       -
phosphonium, triphenylpropenyl-, bromide, (e)- (8ci)       -
QL-X-138       -
QL-XI-92       -
QL-XII-47       -
rhodium dimer       -
SB52334       -
THZ-2-102-1       -
THZ-2-49       -
TL-1-85       -
TL-2-105       -
triacetyl 13,14,15-isocrambescidin 800 hydrochloride       -
VNLG/124       -
WZ3105       -
XMD13-2       -
XMD14-99       -
XMD15-27       -
(z)3,4,5-trimethoxystilbene       -

Interaction Network (The top 100 interactions):


Interactor1: hsv1-miR-H4-5p
Interactor2: C8orf86

Evidence Support:


Prediction-Evidence miRanda//Targetscan
Support Database VmiReg

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