Basic Information:

  VIRBase ID:  

VHID00081548

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H2-3p:  MIMAT0008399          GRWD1:  NM_031485     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H2-3p	GRWD1
miRBase Accession/Entrez ID	MIMAT0008399	83743
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CDW4//GRWD//RRB1//WDR28

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GRWD1	chr19:48952942(+) A-I      intronic chr19:48952951(+) A-I      intronic chr19:48952955(+) A-I      intronic chr19:48952967(+) A-I      intronic chr19:48952957(+) A-I      intronic chr19:48952964(+) A-I      intronic chr19:48952998(+) A-I      intronic chr19:48953003(+) A-I      intronic chr19:48956656(+) A-I      3'UTR chr19:48956707(+) A-I      3'UTR chr19:48950912(+) A-I      intronic chr19:48952366(+) A-I      intronic chr19:48952881(+) A-I      intronic chr19:48952407(+) A-I      intronic chr19:48956720(+) A-I      3'UTR chr19:48956653(+) A-I      3'UTR chr19:48952816(+) A-I      intronic chr19:48956734(+) A-I      3'UTR chr19:48952842(+) A-I      intronic chr19:48956724(+) A-I      3'UTR chr19:48952993(+) A-I      intronic chr19:48950767(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	GRWD1	chr19:48956653(+) A-I exon 3'UTR    15342557 chr19:48950000(+) A-I exon CDS    21960545 chr19:48952893(+) A-I intron -    21960545 chr19:48956653(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GRWD1	chr19:48949042-48949043(+) m6A 5'UTR       24981863 chr19:48949213-48949214(+) m6A 5'UTR//intron       24284625//24981863 chr19:48949298-48949299(+) m6A CDS//exon//intron       24284625//24981863//22575960 chr19:48949306-48949307(+) m6A CDS//exon//intron       24284625//24981863//22575960 chr19:48949445-48949446(+) m6A CDS//exon//intron       24284625//22575960 chr19:48949465-48949466(+) m6A exon//intron       24284625//22575960 chr19:48949686-48949687(+) m6A 5'UTR//CDS//exon       24284625 chr19:48949694-48949695(+) m6A 5'UTR//CDS//exon       24284625 chr19:48949730-48949731(+) m6A 5'UTR//CDS//exon       24284625 chr19:48949971-48949972(+) m6A CDS       24284625//24981863 chr19:48950045-48950046(+) m6A CDS       24284625//24981863 chr19:48953736-48953737(+) m6A CDS       24284625//22575960 chr19:48953952-48953953(+) m6A CDS       24284625//22575960 chr19:48953966-48953967(+) m6A CDS       24284625//22575960 chr19:48953997-48953998(+) m6A CDS       24284625//22575960 chr19:48954036-48954037(+) m6A CDS       24284625//22575960 chr19:48954060-48954061(+) m6A CDS       24284625//22575960 chr19:48954333-48954334(+) m6A CDS       24284625//22575960 chr19:48954471-48954472(+) m6A CDS       24284625//24209618//22575960//22608085 chr19:48956034-48956035(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:48956064-48956065(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:48956085-48956086(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:48956103-48956104(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:48956137-48956138(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:48956183-48956184(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:48956320-48956321(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr19:48956375-48956376(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr19:48956469-48956470(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr19:48956495-48956496(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr19:48956512-48956513(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr19:48956588-48956589(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr19:48956903-48956904(+) m6A 3'UTR       24284625//24209618//24981863 chr19:48956935-48956936(+) m6A 3'UTR       24284625//24209618//24981863//22575960 chr19:48957141-48957142(+) m6A 3'UTR       24284625 chr19:48957170-48957171(+) m6A 3'UTR       24284625 chr19:48957707-48957708(+) m6A 3'UTR       24284625 chr19:48957743-48957744(+) m6A 3'UTR       24284625 chr19:48957750-48957751(+) m6A 3'UTR       24284625 chr19:48958079-48958080(+) m6A 3'UTR       24284625//24981863 chr19:48958196-48958197(+) m6A 3'UTR       24284625//24981863 chr19:48958944-48958945(+) m6A 3'UTR       24981863 chr19:48958966-48958967(+) m6A 3'UTR       24981863 chr19:48958993-48958994(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	GRWD1	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H2-3p
Interactor2: GRWD1

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg