Basic Information:

  VIRBase ID:  

VHID00080436

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H2-3p:  MIMAT0008399          MAT2B:  NM_182796     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H2-3p	MAT2B
miRBase Accession/Entrez ID	MIMAT0008399	27430
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MAT-II//MATIIbeta//Nbla02999//SDR23E1//TGR

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAT2B	chr5:162943217(+) A-I      intronic chr5:162937530(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MAT2B	chr5:162932751(+) T-G exon CDS    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAT2B	chr5:162930223-162930224(+) m6A 5'UTR       24981863 chr5:162930327-162930328(+) m6A 5'UTR//exon       25456834//24981863//22608085 chr5:162930333-162930334(+) m6A 5'UTR//exon       25456834//24981863//22608085 chr5:162930360-162930361(+) m6A 5'UTR//exon       25456834//24981863//22608085 chr5:162930419-162930420(+) m6A CDS//exon       25456834//24981863//22608085 chr5:162945582-162945583(+) Y 3'UTR//exon       25219674

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MAT2B	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H2-3p
Interactor2: MAT2B

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg