Basic Information:

  VIRBase ID:  

VHID00077362

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H2-5p:  MIMAT0008398          IGF2R:  NM_000876     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H2-5p	IGF2R
miRBase Accession/Entrez ID	MIMAT0008398	3482
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CD222//CI-M6PR//CIMPR//M6P-R//M6P/IGF2R//MPR 300//MPR1//MPR300//MPRI

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	IGF2R	chr6:160518507(+) A-I      intronic chr6:160518545(+) A-I      intronic chr6:160518600(+) A-I      intronic chr6:160518487(+) A-I      intronic chr6:160409487(+) A-I      intronic chr6:160520538(+) A-I      intronic chr6:160409362(+) A-I      intronic chr6:160409333(+) A-I      intronic chr6:160409486(+) A-I      intronic chr6:160409490(+) A-I      intronic chr6:160518479(+) A-I      intronic chr6:160473032(+) A-I      intronic chr6:160473035(+) A-I      intronic chr6:160519601(+) A-I      intronic chr6:160474885(+) A-I      intronic chr6:160503566(+) A-I      intronic chr6:160401222(+) A-I      intronic chr6:160408696(+) A-I      intronic chr6:160503578(+) A-I      intronic chr6:160518461(+) A-I      intronic chr6:160519641(+) A-I      intronic chr6:160519644(+) A-I      intronic chr6:160519708(+) A-I      intronic chr6:160519587(+) A-I      intronic chr6:160519724(+) A-I      intronic chr6:160519731(+) A-I      intronic chr6:160519618(+) A-I      intronic chr6:160519747(+) A-I      intronic chr6:160518491(+) A-I      intronic chr6:160518498(+) A-I      intronic chr6:160519665(+) A-I      intronic chr6:160519811(+) A-I      intronic chr6:160520524(+) A-I      intronic chr6:160519744(+) A-I      intronic chr6:160520606(+) A-I      intronic chr6:160519595(+) A-I      intronic chr6:160472919(+) A-I      intronic chr6:160409432(+) A-I      intronic chr6:160519792(+) A-I      intronic chr6:160502128(+) A-I      intronic chr6:160473027(+) A-I      intronic chr6:160501895(+) A-I      intronic chr6:160474844(+) A-I      intronic chr6:160519602(+) A-I      intronic chr6:160474843(+) A-I      intronic chr6:160474873(+) A-I      intronic chr6:160508970(+) A-I      intronic chr6:160474979(+) A-I      intronic chr6:160408447(+) A-I      intronic chr6:160472800(+) A-I      intronic chr6:160472809(+) A-I      intronic chr6:160421868(+) A-I      intronic chr6:160409426(+) A-I      intronic chr6:160518636(+) A-I      intronic chr6:160474960(+) A-I      intronic chr6:160454352(+) A-I      intronic chr6:160474950(+) A-I      intronic chr6:160474986(+) A-I      intronic chr6:160519740(+) A-I      intronic chr6:160473056(+) A-I      intronic chr6:160472873(+) A-I      intronic chr6:160474818(+) A-I      intronic chr6:160521844(+) A-I      intronic chr6:160392927(+) A-I      intronic chr6:160407406(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	IGF2R	chr6:160433599(+) A-G intron -    22484847 chr6:160433600(+) A-G intron -    22484847 chr6:160433614(+) A-G intron -    22484847 chr6:160407303(+) A-G intron -    22484847 chr6:160407467(+) T-G intron -    22484847 chr6:160408447(+) A-G intron -    22484847 chr6:160408517(+) A-G intron -    22484847 chr6:160450169(+) T-C intron -    22484847 chr6:160472800(+) A-G intron -    22484847 chr6:160472809(+) A-G intron -    22484847 chr6:160474823(+) A-G intron -    22484847 chr6:160474844(+) A-G intron -    22484847 chr6:160474931(+) A-G intron -    22484847 chr6:160474979(+) A-G intron -    22484847 chr6:160503359(+) G-T intron -    22484847 chr6:160518562(+) A-G intron -    22484847 chr6:160519573(+) A-G intron -    22484847 chr6:160519595(+) A-G intron -    22484847 chr6:160519596(+) A-G intron -    22484847 chr6:160519602(+) A-G intron -    22484847 chr6:160519730(+) A-G intron -    22484847 chr6:160521841(+) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	IGF2R	chr6:160412333-160412334(+) m6A CDS       27773535 chr6:160464223-160464224(+) m6A CDS       22575960 chr6:160466805-160466806(+) m6A CDS       27773535 chr6:160482913-160482914(+) m6A CDS       27773535 chr6:160483640-160483641(+) Cm CDS       - chr6:160485480-160485481(+) m6A CDS       26404942 chr6:160485495-160485496(+) m6A CDS       26404942 chr6:160492975-160492976(+) m6A CDS       22575960 chr6:160500683-160500684(+) Am CDS       - chr6:160505094-160505095(+) m6A CDS       26404942 chr6:160510229-160510230(+) m6A CDS       27773535 chr6:160510967-160510968(+) m6A CDS       27773535 chr6:160510975-160510976(+) m6A CDS       27773535 chr6:160510985-160510986(+) m6A CDS       27773535 chr6:160511033-160511034(+) m6A CDS       27773535 chr6:160514511-160514512(+) m6A intron       22608085 chr6:160514566-160514567(+) m6A intron       24284625//25456834//24981863//22608085 chr6:160514578-160514579(+) m6A intron       24284625//25456834//24981863//22608085 chr6:160514605-160514606(+) m6A intron       24284625//25456834//24981863//22608085 chr6:160514628-160514629(+) m6A intron       24284625//25456834//24981863//22608085 chr6:160514664-160514665(+) m6A intron       24284625//25456834//22608085 chr6:160514673-160514674(+) m6A intron       24284625//25456834//22608085 chr6:160514693-160514694(+) m6A intron       24284625//25456834//22608085 chr6:160514711-160514712(+) m6A intron       24284625//22608085 chr6:160514749-160514750(+) m6A intron       22608085 chr6:160514755-160514756(+) m6A intron       22608085 chr6:160514779-160514780(+) m6A intron       - chr6:160514907-160514908(+) m6A intron       24284625//22608085 chr6:160514912-160514913(+) m6A intron       24284625//24981863//22608085 chr6:160514940-160514941(+) m6A intron       24284625//24981863//22608085 chr6:160514963-160514964(+) m6A intron       24284625//24981863//22608085 chr6:160514997-160514998(+) m6A intron       24284625//25456834//24981863//22608085 chr6:160515031-160515032(+) m6A intron       24284625//25456834//24981863//22608085 chr6:160515042-160515043(+) m6A intron       24284625//24981863//22608085 chr6:160515076-160515077(+) m6A intron       24284625//24981863//22608085 chr6:160524781-160524782(+) m6A CDS//exon       24284625//24981863//27773535 chr6:160525718-160525719(+) m1A CDS//intron       26863196 chr6:160525723-160525724(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535 chr6:160525738-160525739(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535 chr6:160525862-160525863(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:160526050-160526051(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:160526099-160526100(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:160526152-160526153(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:160526179-160526180(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:160526222-160526223(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr6:160526406-160526407(+) m6A 3'UTR//intron       24284625//24209618//24981863 chr6:160526428-160526429(+) m6A 3'UTR//intron       24284625//24981863 chr6:160526546-160526547(+) m6A 3'UTR//intron       26404942 chr6:160527145-160527146(+) m6A 3'UTR//intron       25456834 chr6:160527395-160527396(+) m6A 3'UTR//intron       24209618 chr6:160527423-160527424(+) m6A 3'UTR//intron       24209618 chr6:160531543-160531544(+) m6A 3'UTR//intron       22608085 chr6:160531569-160531570(+) m6A 3'UTR//intron       22608085 chr6:160531822-160531823(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr6:160531848-160531849(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr6:160531905-160531906(+) m6A 3'UTR//intron       24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	IGF2R	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)|K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H2-5p
Interactor2: IGF2R

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg