Basic Information:

  VIRBase ID:  

VHID00075368

  Virus:  

Human alphaherpesvirus 1 (HSV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hsv1-miR-H1-5p:  MIMAT0003744          SIDT2:  NM_001040455     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsv1-miR-H1-5p	SIDT2
miRBase Accession/Entrez ID	MIMAT0003744	51092
Organism	Human alphaherpesvirus 1 (HSV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CGI-40

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SIDT2	chr11:117056435(+) A-I      intronic chr11:117056438(+) A-I      intronic chr11:117056479(+) A-I      intronic chr11:117056465(+) A-I      intronic chr11:117056444(+) A-I      intronic chr11:117056443(+) A-I      intronic chr11:117056388(+) A-I      intronic chr11:117056384(+) A-I      intronic chr11:117056434(+) A-I      intronic chr11:117056408(+) A-I      intronic chr11:117056392(+) A-I      intronic chr11:117056447(+) A-I      intronic chr11:117056393(+) A-I      intronic chr11:117056412(+) A-I      intronic chr11:117056380(+) A-I      intronic chr11:117055907(+) A-I      intronic chr11:117056436(+) A-I      intronic chr11:117056487(+) A-I      intronic chr11:117056429(+) A-I      intronic chr11:117056439(+) A-I      intronic chr11:117056473(+) A-I      intronic chr11:117055972(+) A-I      intronic chr11:117056336(+) A-I      intronic chr11:117064784(+) A-I      intronic chr11:117056490(+) A-I      intronic chr11:117055955(+) A-I      intronic chr11:117055964(+) A-I      intronic chr11:117055952(+) A-I      intronic chr11:117056503(+) A-I      intronic chr11:117056398(+) A-I      intronic chr11:117055516(+) A-I      intronic chr11:117055640(+) A-I      intronic chr11:117056483(+) A-I      intronic chr11:117056339(+) A-I      intronic chr11:117055716(+) A-I      intronic chr11:117056338(+) A-I      intronic chr11:117056515(+) A-I      intronic chr11:117056404(+) A-I      intronic chr11:117056569(+) A-I      intronic chr11:117056038(+) A-I      intronic chr11:117056451(+) A-I      intronic chr11:117056550(+) A-I      intronic chr11:117056423(+) A-I      intronic chr11:117055461(+) A-I      intronic chr11:117056432(+) A-I      intronic chr11:117056510(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SIDT2	chr11:117055640(+) A-G intron -    22484847 chr11:117056473(+) A-G intron -    22484847 chr11:117061891(+) G-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SIDT2	chr11:117049517-117049518(+) m6A 5'UTR       24284625//24209618//24981863 chr11:117049729-117049730(+) m6A 5'UTR//intron       - chr11:117049795-117049796(+) m6A 5'UTR//intron       - chr11:117049829-117049830(+) m6A 5'UTR//intron       - chr11:117050454-117050455(+) m6A 5'UTR//intron       - chr11:117052170-117052171(+) Cm 5'UTR//CDS//exon//intron       - chr11:117052559-117052560(+) m6A 5'UTR//CDS//exon//intron       - chr11:117061416-117061417(+) Y CDS//exon//intron       26075521 chr11:117062593-117062594(+) m6A CDS//exon       - chr11:117066838-117066839(+) m6A 3'UTR//intron       22608085 chr11:117066905-117066906(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr11:117066936-117066937(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr11:117066957-117066958(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr11:117067002-117067003(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr11:117067112-117067113(+) m6A 3'UTR//intron       24284625 chr11:117067397-117067398(+) Y 3'UTR//intron       26075521 chr11:117067463-117067464(+) m6A 3'UTR//intron       25456834 chr11:117067524-117067525(+) m6A 3'UTR//intron       25456834 chr11:117067542-117067543(+) m6A 3'UTR//intron       25456834 chr11:117067603-117067604(+) m6A 3'UTR//intron       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsv1-miR-H1-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	SIDT2	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsv1-miR-H1-5p
Interactor2: SIDT2

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg