Basic Information:
VIRBase ID: VHID00070227
Virus: Gallid alphaherpesvirus 2
Host: Gallus gallus
Confidence Score: 0.9526
Interaction Type: Virus-Host interaction
Predicted Binding:
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Interaction Network (The top 100 interactions) :
Interactor1: mdv1-miR-M4-3p
Interactor2: SPI1
Evidence Support:
Strong-Evidence
Dual luciferase reporter assay//IP//Western blot
Support Database
ViRBase
References:
PMID
31189706
Target region
3'UTR
Source
ViRBase
Interactor1 expression
Downregulation
Tissue or cell line
HP8 cells
Interactor2 expression
Upregulation
Description
Results from the reporter assay and direct expression analysis of the Pu.1 target thus confirmed the deletion of miR-M4 and the functional consequences in the mutant C48 clone.