Detail Information

Basic Information:


  VIRBase ID:  

VHID00070092

  Virus:  

Gallid alphaherpesvirus 2

  Host:  

Gallus gallus

  Confidence Score:  

0.8847

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol mdv1-miR-M4-5p RPS6KA3
miRBase
Accession/Entrez ID		 MIMAT0003924 418605
Organism Gallid alphaherpesvirus 2 Gallus gallus
Category miRNA mRNA
Alias - -

Interaction Network (The top 100 interactions):


Interactor1: mdv1-miR-M4-5p
Interactor2: RPS6KA3

Evidence Support:


Strong-Evidence Luciferase reporter assay
Weak-Evidence PAR-CLIP
Prediction-Evidence PARalyzer
Support Database VIRmiRNA//VmiReg

References:


PMID 24449754 Target region 3'UTR
Source VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line 293T cells//MSB1 cells Interactor2 expression None
Description As may be observed, we detected significant and selective repression of FLuc expression mediated by these 3'UTRs that was partially or entirely alleviated by mutation of the predicted miR-M4/miR-155 target sites.

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