Basic Information:
VIRBase ID: VHID00070056
Virus: Gallid alphaherpesvirus 2
Host: Gallus gallus
Confidence Score: 0.7311
Interaction Type: Virus-Host interaction
Predicted Binding:
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Interactor Information:
Interactor1
Interactor2
Symbol
mdv1-miR-M4-5p
RORA
miRBase Accession/Entrez ID
MIMAT0003924
415377
Organism
Gallid alphaherpesvirus 2
Gallus gallus
Category
miRNA
mRNA
Alias
-
RORalpha1
Interaction Network (The top 100 interactions) :
Interactor1: mdv1-miR-M4-5p
Interactor2: RORA
Evidence Support:
Strong-Evidence
Luciferase reporter assay
Support Database
VmiReg
References:
PMID
24449754
Target region
3'UTR
Source
VmiReg
Interactor1 expression
None
Tissue or cell line
293T cells
Interactor2 expression
None
Description
As may be observed, we detected significant and selective repression of FLuc expression mediated by these 3'UTRs that was partially or entirely alleviated by mutation of the predicted miR-M4/miR-155 target sites.