Detail Information

Basic Information:


  VIRBase ID:  

VHID00066576

  Virus:  

Zika virus (ZIKV)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol zikv-mir-8 BIRC8
miRBase
Accession/Entrez ID		 zikv-mir-8 112401
Organism Zika virus (ZIKV) Homo sapiens
Category miRNA pseudo
Alias - hILP2//ILP-2//ILP2//RNF136

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug BIRC8
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222
6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile       9956119
Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773
5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride       9938202
1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054
Tivozanib       9911830
Zibotentan       9910224
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786
PI-103       9884685
2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide       9874913
2-(((5-(4-(4-(3-Fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)furan-2-yl)methyl)(2-(methylsulfonyl)ethyl)amino)acetonitrile       9873849
Osi-930       9868037
5Z-7-Oxozeaenol       9863776
2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940
Midostaurin       9829523
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528
1,5-Diazabicyclo(3.2.1)octane, 8-(4-pyridyl)-       96625
9H-Purine, 6-(ethylthio)-9-beta-D-ribofuranosyl-(8CI)(9CI)       95846
6-Benzylthioinosine       95263
1-(2-Thiazolylazo)-2-naphthol       93572
8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acid       92577
Pentamidine isethionate       8813
Acridine Yellow G       8672
Sulfonaphtholazoresorcinol       85517
Benzethonium chloride       8478
Phenformin       8249
(E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717
Piperidinium pentamethylenedithiocarbamate       72508
N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473
(S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848
Belinostat       6918638
2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide       6918454
Daporinad       6914657
N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167
1-(2-Pyridylazo)-2-naphthol       6825
Brigatinib       68165256
Triciribine       65399
2-Amino-6-methoxypurine       65275
AICA ribonucleotide       65110
Tanespimycin       6505803
Digitin       6474107
Ispinesib mesylate       6450816
Axitinib       6450551
Pelitinib       6445562
Dacinostat       6445533
Mycothiazole       6443333
4-(N-Hydroxyacetamido)stilbene       6433723
Cytarabine       6253
Gemcitabine       60750
Mitomycin       5746
3-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol;hydrochloride       57399804
5-[2-[4-(Aminomethyl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2-chlorophenol;hydrochloride       57399803
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)       57339144
1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea       56962337
Dimethyloxalylglycine       560326
Phyllanthastatin 1       5477587
Viridenomycin       54686463
2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid       54685215
Lfm-a13       54676905
Stipiamide       5467322
Mito-tempol       54613387
Olivomycin Transformation       54610760
Eupalmerin acetate       5459169
Thiram       5455
Temozolomide       5394
Bleomycin a2       5360373
Cycliramine maleate       5357113
Rubremetinium chloride       5351504
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664
Palbociclib       5330286
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methylbenzamide       53302361
Bosutinib       5328940
Vorinostat       5311
5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione       5289247
2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one       5278396
Bis(2-hydroxy-1-naphthyl) disulfide       521106
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide       5113032
Alsterpaullone       5005498
Tubastatin A       49850262
Alectinib       49806720
Cardiovite       4951
Shikonin       479503
Pentamidine       4735
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432
(S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate       46907787
3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626
Avagacestat       46883536
2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine       46224516
N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454
N-Methyl-1,5-bis(4-cyanophenoxy)-3-aza-pentane       45028719
N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912
Okadaic acid       446512
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660
Tretinoin       444795
Dabrafenib       44462760
Cyclamin       441916
Refametinib       44182295
2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid       44137675
Ouabain       439501
Foretinib       42642645
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640
(2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol       42623900
Vemurafenib       42611257
Vilangin       417182
1,6-Bis[4-(4-aminophenoxy)phenyl]diamantane       397904
Leflunomide       3899
Tetra-p-anisidyl-oxalamidine       388030
2-(4-Fluorophenyl)-5-methyl-1H-1,8-naphthyridin-4-one       386576
2,6-Dibromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol       3796
2,3,6-Tribromo-7-chloro-3,7-dimethyloct-1-ene       377930
N-Hydroxytetradecanamide       366134
Etoposide       36462
Paclitaxel       36314
1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)-       362170
3,4-Dihydroxynaphthalene-2-carboxylic acid       356138
2,3-Dimethylbenzo[g]quinoxaline-5,10-dione       353644
5-Fluorouracil       3385
1,4-Benzenediamine, N1-9-acridinyl-2-methoxy-       334401
Doxorubicin       31703
Clomifene citrate       3033832
Tamoxifen       2733526
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965
2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557
4-[3-Fluoro-5-(4-morpholinyl)phenyl]-N-[4-[3-(4-morpholinyl)-1,2,4-triazol-1-yl]phenyl]-2-pyrimidinamine       25222038
4-Fluoro-2-[(2-{[2-methoxy-4-(1-propyl-4-piperidinyl)phenyl]amino}-1H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]benzamide       25218601
1-(4-Bromophenyl)-3-(1H-indazol-3-yl)urea       25197647
Omipalisib       25167777
Ruxolitinib       25126798
Cabozantinib       25102847
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid       25022668
Navitoclax       24978538
MK-2206       24964624
Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314
Quizartinib       24889392
Fluorene, 9-bromo-2,4,7-trichloro-       248608
Ponatinib       24826799
Vismodegib       24776445
4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860
Cudc-101       24756910
Antimycin A3       245869
Vincaleukoblastine       241903
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719
2-Chloro-3-[(furan-2-ylmethyl)amino]naphthalene-1,4-dione       239677
Bicalutamide       2375
Olaparib       23725625
(2E,5E)-2,5-Bis(thiophen-2-ylmethylene)cyclopentanone       2314623
Aristolochic acid       2236
6-Chloro-2-methoxy-9-[(5-piperidinopentyl)amino]acridine       219600
7-(alpha-Anilino-P-nitrobenzyl)-8-quinolinol       219565
Nutlin-3       216345
Lenalidomide       216326
Buthionine sulfoximine       21157
8-Amino-5-methyl-6-phenylphenanthridin-5-ium bromide       21144180
N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine       2051
Kinetin riboside       20345
Hemigossypolone       182249
8-Chloro-cyclicamp       17856967
Pictilisib       17755052
Enzastaurin       176167
4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388
Gsk-690693       16725726
Fedratinib       16722836
Mercury, (acetyloxy)(pentamethylphenyl)-       16683786
2,4-cis-Asimicinone       159566
Docetaxel       148124
1-(Tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea       1401
N-[5-[5-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-pyridin-4-ylfuran-3-yl]-2,3-dihydroinden-1-ylidene]hydroxylamine;hydrochloride       136207967
4-[(5z)-5-(1-Nitroso-2,3-Dihydro-5h-Inden-5-Ylidene)-2-(Piperidin-4-Yl)-3,5-Dihydro-4h-Imidazol-4-Ylidene]-1,4-Dihydropyridine       136026031
Astrazon Orange R       135747272
(Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062
N,N-Dimethyl-2-[4-[4-(1-nitroso-2,3-dihydroinden-5-ylidene)-5-(1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine       135564599
Luminespib       135539077
Pac-1       135421197
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one       135418940
Osi-027       135398516
Akt inhibitor VIII       135398501
Ortho-topolin riboside       13506406
Methotrexate       126941
Lestaurtinib       126565
Berberine chloride       12456
Veliparib       11960529
(Z)-But-2-enedioic acid;3-[4-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]-N-methylpropanamide       11954261
Silvestrol       11787114
BAY 61-3606 dihydrochloride       11784504
N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511
Trametinib       11707110
4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372
4-[2-(2-Chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide       11634725
Idelalisib       11625818
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559
Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964
5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598
Linifanib       11485656
Nvp-aew541       11476171
Bafetinib       11387605
N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846
4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide       11338033
8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430
Pararosaniline hydrochloride       11292
Amuvatinib       11282283
Sepantronium bromide       11178236
1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole       11162021
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667
Quinine (Hydrobromide)       11068
Setoglaucine       107404
[(4-Methylphenyl)methyl](triphenyl)arsanium bromide       10672721
7-Ethyl-10-hydroxycamptothecin       104842
Plicatic acid       104836
5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4h-Chromen-3-Yl 3,4-Di-O-Acetyl-6-Deoxy-alpha-L-Mannopyranoside       10459196
VX-702       10341154
Afatinib       10184653
Selumetinib       10127622
N-(3-{[5-Iodo-4-({3-[(Thiophen-2-Ylcarbonyl)amino]propyl}amino)pyrimidin-2-Yl]amino}phenyl)pyrrolidine-1-Carboxamide       10077147
Pyrazine, 2,2'-(o-chlorobenzylidenediimino)di-       100764
Masitinib       10074640
Tocladesine       100299
PDK1 inhibitor AR-12       10027278
1,4-dimethoxy-7-azaisoindole[2,1-a]quinoxalin-6(5h)-one       -
;2-(3-((2-methoxybenzyl)amino)propyl)-7-(3-((4-((3-(meth...       -
;2-(3-aminopropyl)-7-(3-((2-methoxybenzyl)amino)propyl)b...       -
;3-amino-6-ethyl-N-(3-fluorophenyl)-5,6,7,8-tetrahydroth...       -
;4-fluoro-N-(3-(4-(6-(4-hydroxyphenyl)imidazo[2,1-b]thia...       -
5,6-ethylenediquino[3,2-b       -
;7-(2-chlorophenyl)-2-methoxy-3-(phenylsulfonyl)-6,7-dih...       -
.alpha.-sarcin       -
antibiotic 2-79-a(5)       -
Basic Fuchsin       -
benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 3-methyl-       -
benzo[b]naphtho[2,3-d]furan-6,11-dione, 4-chloro-3-hydroxy       -
Bleomycin (50 uM)       -
Genentech Cpd 10       -
gramicidin       -
g-tpp       -
ICL1100013       -
JW-7-24-1       -
KIN001-236       -
KIN001-244       -
KIN001-260       -
KIN001-266       -
KIN001-270       -
MPS-1-IN-1       -
naphth[2,3-d]oxazol-9-one, 2-methyl-4-(phenylimino)-       -
naphtho[2,1-b]quinolizinium, 5-chloro-7-methyl- perchlorate       -
naphtho[2,3-b]furan-4,9-dione, 2-bromo-       -
naphtho[2,3-d]thiazole-4,9-dione, 3-methyl-2-(methylimino)-       -
N-methyl-N-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)-4-(2,6...       -
NPK76-II-72-1       -
Nutlin-3a (-)       -
o-xylenebis-(triphenylphosphonium bromide)       -
pararosaniline pamoate       -
protein toxin a 23 - mw approx. 6700       -
protein toxin c 10 - mw approx. 6700       -
QL-X-138       -
QL-XI-92       -
QL-XII-47       -
;(R)-4,11-dihydroxy-3-((pyrrolidin-3-ylamino)methyl)-1H-...       -
rhodium dimer       -
riboprine(usan)       -
rTRAIL       -
SB52334       -
THZ-2-102-1       -
THZ-2-49       -
TL-1-85       -
TL-2-105       -
tp38-279       -
Tyrothricin       -
Vinorelbine       -
VNLG/124       -
WZ3105       -
XMD13-2       -
XMD14-99       -
XMD15-27       -
;(Z)-5-Chloro-2-(1-methyl-5-nitroimidazole-2-ylmethylene...       -
;(Z)-6-Chloro-2-(1-methyl-4-nitroimidazole-5-ylmethylene...       -

Interaction Network (The top 100 interactions):


Interactor1: zikv-mir-8
Interactor2: BIRC8

Evidence Support:


Prediction-Evidence miRanda
Support Database ZIKV-CDB

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