Detail Information

Basic Information:


  VIRBase ID:  

HVID00010676

  Virus:  

SARS-CoV-2 (USA-WA1/2020)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-5197-3p S
miRBase
Accession/Entrez ID
MIMAT0021131 S
Organism Homo sapiens SARS-CoV-2 (USA-WA1/2020)
Category miRNA mRNA
Alias -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-5197-3p
rs1347866830 chr5:143679936    G/C
rs1405555825 chr5:143679942    G/A
rs1411653302 chr5:143679932    C/A
rs892818585 chr5:143679941    C/T
rs77549240 chr5:143679930    G/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-5197-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-5197-3p
Interactor2: S

Evidence Support:


Prediction-Evidence FIMO
Support Database ViRBase

References:


PMID 32676599 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Human lung epithelial cells Interactor2 expression None
Description In this study, we used computational approach to investigate the potential binding sites of human miRs in SARS-CoV-2 genome using FIMO [82]. We identified 22 miRNAs that could potentially bind throughout the length of the SARS-CoV2 viral genome.

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