Detail Information

Basic Information:


  VIRBase ID:  

HVID00010670

  Virus:  

SARS-CoV-2 (USA-WA1/2020)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374a-3p ORF1ab
miRBase
Accession/Entrez ID		 MIMAT0004688 ORF1ab
Organism Homo sapiens SARS-CoV-2 (USA-WA1/2020)
Category miRNA mRNA
Alias -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-374a-3p
rs766292977 chrX:74287300    C/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374a-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374a-3p
Interactor2: ORF1ab

Evidence Support:


Prediction-Evidence FIMO
Support Database ViRBase

References:


PMID 32676599 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Human lung epithelial cells Interactor2 expression None
Description In this study, we used computational approach to investigate the potential binding sites of human miRs in SARS-CoV-2 genome using FIMO [82]. We identified 22 miRNAs that could potentially bind throughout the length of the SARS-CoV2 viral genome.

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