Detail Information

Basic Information:


  VIRBase ID:  

HVID00010661

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-12129 ORF8
miRBase
Accession/Entrez ID		 MIMAT0049023 43740577
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp09

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-12129
rs1444295235 chrX:153335526    T/A
rs1444295235 chrX:153335526    T/C
rs1556960531 chrX:153335529    G/A
rs188387506 chrX:153335518    G/C
rs1372829750 chrX:153335517    T/G

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-12129
Interactor2: ORF8

Evidence Support:


Prediction-Evidence IntaRNA//miRanda//miRBase//psRNATarget
Support Database ViRBase

References:


[1]PMID 32547891 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Among 2,654 mature entries of Homo sapiens in miRBase Release 22.1, 479 of them could target SARS-CoV-2 genes (Supplemental Files-human to virus). While Envelope and ORF6 genes were targeted by single miRNAs, ORF1ab appeared to be the target of 369 different human mature miRNAs (Table 2).
[2]PMID 32765592 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description From our rigorous analysis pipeline, which covers three different well-established algorithms (IntaRNA, miRanda, and psRNATarget) to predict RNA-RNA interactions, we have identified 122 and 106 host antiviral miRNAs against SARS-CoV (R) and SARS-CoV-2 (R), respectively (Figures 2A,B, Supplementary File 2).

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