Detail Information

Basic Information:


  VIRBase ID:  

HVID00010292

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-215-3p M
miRBase
Accession/Entrez ID		 MIMAT0026476 43740571
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp05

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-215-3p
rs1333471638 chr1:220117882    G/A
rs749489380 chr1:220117883    C/G
rs754286532 chr1:220117889    GA/G
rs1345487830 chr1:220117895    A/G
rs757646667 chr1:220117893    TGACA/T
rs768393822 chr1:220117898    G/A

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-215-3p
Exosome HCC cell line (Hep3B|HepG2|PLC/PRF/5)     21721029
Exosome Ovarian follicular fluid     22116803
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-215-3p
Interactor2: M

Evidence Support:


Prediction-Evidence miRBase
Support Database ViRBase

References:


PMID 32547891 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Among 2,654 mature entries of Homo sapiens in miRBase Release 22.1, 479 of them could target SARS-CoV-2 genes (Supplemental Files-human to virus). While Envelope and ORF6 genes were targeted by single miRNAs, ORF1ab appeared to be the target of 369 different human mature miRNAs (Table 2).

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