Detail Information

Basic Information:


  VIRBase ID:  

HVID00010066

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-4732-5p ORF8
miRBase
Accession/Entrez ID		 MIMAT0019855 43740577
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp09

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-4732-5p
rs1221758243 chr17:28861711    C/T
rs1282565841 chr17:28861713    C/T
rs1284341041 chr17:28861708    G/A
rs1352947256 chr17:28861701    G/T
rs1380889672 chr17:28861710    T/A
rs1413647390 chr17:28861707    T/TG
rs762363998 chr17:28861705    C/A
rs1043420842 chr17:28861716    C/A
rs1217937677 chr17:28861721    C/T
rs758352089 chr17:28861718    C/G
rs758352089 chr17:28861718    C/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-4732-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-4732-5p
Interactor2: ORF8

Evidence Support:


Prediction-Evidence IntaRNA//miRanda//psRNATarget
Support Database ViRBase

References:


PMID 32765592 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description From our rigorous analysis pipeline, which covers three different well-established algorithms (IntaRNA, miRanda, and psRNATarget) to predict RNA-RNA interactions, we have identified 122 and 106 host antiviral miRNAs against SARS-CoV (R) and SARS-CoV-2 (R), respectively (Figures 2A,B, Supplementary File 2).

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