Detail

Detail Information

Basic Information:

VIRBase ID:

HVID00009699

Virus:

SARS-CoV-2 (NC_045512.2)

Host:

Homo sapiens

Confidence Score:

0.1828

Interaction Type:

Host-Virus interaction

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-764	ORF1ab
miRBase Accession/Entrez ID	MIMAT0010367	43740578
Organism	Homo sapiens	SARS-CoV-2 (NC_045512.2)
Category	miRNA	mRNA
Alias	-	GU280_gp01

ncRNA SNP information:

Resource

Symbol

SNP ID

SNP Position

Ref/Alt

miRNASNP-v3

hsa-miR-764

rs1287058792	chrX:114639445	G/A
rs1454319111	chrX:114639462	C/A
rs1454319111	chrX:114639462	C/T
rs377648254	chrX:114639464	C/T
rs781904343	chrX:114639450	T/G

RNA Localization:

Resource

Symbol

Subcellular Localization

Tissue or Cell Line

PMID

RNALocate

hsa-miR-764

Exosome	Breast milk\|Cell lines\|Epididymal epithelial cells\|Osteoblast\|Plasma\|Primary glioblastoma neurosphere cells\|Primary keratinocyte\|Saliva\|Serum\|Urine	-
Microvesicle	Cell lines(GBM46\|GBM8\|HaCaT\|K562\|MCF-10A\|MCF-7\|MGG75)\|Plasma\|Primary glioblastoma neurosphere cells\|Primary keratinocytes	-

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-764

Interactor2: ORF1ab

Evidence Support:

Prediction-Evidence	miRanda
Support Database	ViRBase

References:

[1]PMID	33251388	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	Among the 2654 human mature miRNAs, 444 miRNAs were identified with direct binding site on different positions along with the coronavirus 2 reference genome (Table S1).

[2]PMID	33173539	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	We identified 1,018 miRNAs to target SARS-CoV-2 genes, among which 98 miRNAs are predicted to target SARS-CoV-2 genes uniquely when compared with other viruses studied here (Supplementary Table S6).

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