Detail Information

Basic Information:


  VIRBase ID:  

HVID00009659

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1307-3p 3'UTR
miRBase
Accession/Entrez ID		 MIMAT0005951 3'UTR
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1307-3p
rs1426092734 chr10:103394310    C/CG
rs1481938984 chr10:103394311    G/A
rs752363844 chr10:103394304    G/A
rs752363844 chr10:103394304    G/C
rs757783218 chr10:103394308    G/A
rs757783218 chr10:103394308    G/C
rs757783218 chr10:103394308    G/T
rs777377534 chr10:103394310    C/T
rs1447713037 chr10:103394316    G/A
rs1485064361 chr10:103394319    G/A
rs774451000 chr10:103394315    C/A
rs774451000 chr10:103394315    C/G
rs774451000 chr10:103394315    C/T
rs781103034 chr10:103394321    G/A
rs953336177 chr10:103394318    C/A
rs953336177 chr10:103394318    C/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1307-3p
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Plasma     29130611
Exosome Plasma     23663360
Exosome Endothelial cells|Epithelial cells|Lymphoma tissue     -
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-1307-3p
Gemcitabine 60750 Drug interaction    RC00007862
5-Fluorouracil 3385 Drug interaction    RC00007861
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007860
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-1307-3p
Cisplatin 5702198       26676926

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1307-3p
Interactor2: 3'UTR

Evidence Support:


Prediction-Evidence miRanda//miRTarP
Support Database ViRBase

References:


[1]PMID 33801496 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Additionally, if targets are selected by both tools in at least two strains of SARS-CoV-2, we only considered them as potential targets of miRNA on SARS-CoV-2 (Table S2). In Table 1, we present the list of miRNAs meeting all these criteria.
[2]PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description We identified 1,018 miRNAs to target SARS-CoV-2 genes, among which 98 miRNAs are predicted to target SARS-CoV-2 genes uniquely when compared with other viruses studied here (Supplementary Table S6).

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