Detail Information

Basic Information:


  VIRBase ID:  

HVID00009529

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-342-5p N
miRBase
Accession/Entrez ID		 MIMAT0004694 43740575
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp10

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-342-5p
rs1314257099 chr14:100109686    G/A
rs1393913344 chr14:100109691    T/G
rs1416401513 chr14:100109682    A/G
rs1440243721 chr14:100109690    T/C
rs1171193472 chr14:100109674    G/A
rs1171193472 chr14:100109674    G/C
rs1258216912 chr14:100109676    G/T
rs1434812614 chr14:100109677    G/A
rs752423769 chr14:100109675    G/A

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-342-5p
Exosome Primary dendritic cells     21505438
Exosome Plasma     23663360
Exosome Plasma|Serum     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-342-5p
D-Glucose 5793 Drug interaction    RC00007084
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-342-5p
Etoposide 36462       23028896

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-342-5p
Interactor2: N

Evidence Support:


Prediction-Evidence miRanda//miRBase
Support Database ViRBase

References:


[1]PMID 32547891 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Among 2,654 mature entries of Homo sapiens in miRBase Release 22.1, 479 of them could target SARS-CoV-2 genes (Supplemental Files-human to virus). While Envelope and ORF6 genes were targeted by single miRNAs, ORF1ab appeared to be the target of 369 different human mature miRNAs (Table 2).
[2]PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description We identified 1,018 miRNAs to target SARS-CoV-2 genes, among which 98 miRNAs are predicted to target SARS-CoV-2 genes uniquely when compared with other viruses studied here (Supplementary Table S6).

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