Detail Information

Basic Information:


  VIRBase ID:  

HVID00009525

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374a-3p S
miRBase
Accession/Entrez ID		 MIMAT0004688 43740568
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp02//spike glycoprotein

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-374a-3p
rs766292977 chrX:74287300    C/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374a-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374a-3p
Interactor2: S

Evidence Support:


Prediction-Evidence miRBase
Support Database ViRBase

References:


PMID 32547891 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Among 2,654 mature entries of Homo sapiens in miRBase Release 22.1, 479 of them could target SARS-CoV-2 genes (Supplemental Files-human to virus). While Envelope and ORF6 genes were targeted by single miRNAs, ORF1ab appeared to be the target of 369 different human mature miRNAs (Table 2).

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