Detail Information

Basic Information:


  VIRBase ID:  

HVID00009459

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-297 ORF1ab
miRBase
Accession/Entrez ID		 MIMAT0004450 43740578
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp01

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-297
rs112636147 chr4:110860629    A/G
rs1178786327 chr4:110860624    C/T
rs1308294147 chr4:110860628    C/T
rs1311419982 chr4:110860644    T/C
rs574662005 chr4:110860634    C/T
rs750616026 chr4:110860632    T/G
rs761952094 chr4:110860626    T/C
rs765617048 chr4:110860627    G/A
rs766797585 chr4:110860633    G/GCACATT
rs780526713 chr4:110860635    A/G
rs1220881742 chr4:110860636    CACAT/C
rs1296788843 chr4:110860638    C/T
rs1299039069 chr4:110860640    T/C

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-297
Exosome Serum     18589210
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-297
Interactor2: ORF1ab

Evidence Support:


Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description We identified 1,018 miRNAs to target SARS-CoV-2 genes, among which 98 miRNAs are predicted to target SARS-CoV-2 genes uniquely when compared with other viruses studied here (Supplementary Table S6).

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