Detail Information

Basic Information:


  VIRBase ID:  

HVID00009389

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-579-3p ORF1ab
miRBase
Accession/Entrez ID		 MIMAT0003244 43740578
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp01

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-579-3p
rs1165224671 chr5:32394404    T/C
rs1190752232 chr5:32394395    C/T
rs1404190650 chr5:32394401    T/C
rs1412824363 chr5:32394357    AAAGACCATAGACTGTAGTAAGTTGATGCAAAAATAATCGCGG/A
rs1415619084 chr5:32394406    C/T
rs376231726 chr5:32394397    C/T
rs768681140 chr5:32394396    G/A
rs939936972 chr5:32394398    G/A
rs1487016067 chr5:32394410    A/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-579-3p
Exosome Lung adenocarcinoma epithelial cell line (A549)     20615901
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Fibroblasts|Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-579-3p
Interactor2: ORF1ab

Evidence Support:


Prediction-Evidence miRanda
Support Database ViRBase

References:


[1]PMID 33251388 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Among the 2654 human mature miRNAs, 444 miRNAs were identified with direct binding site on different positions along with the coronavirus 2 reference genome (Table S1).
[2]PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description We identified 1,018 miRNAs to target SARS-CoV-2 genes, among which 98 miRNAs are predicted to target SARS-CoV-2 genes uniquely when compared with other viruses studied here (Supplementary Table S6).

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