Detail Information

Basic Information:


  VIRBase ID:  

HVID00009301

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-369-3p ORF8
miRBase
Accession/Entrez ID		 MIMAT0000721 43740577
Organism Homo sapiens SARS-CoV-2 (NC_045512.2)
Category miRNA mRNA
Alias - GU280_gp09

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-369-3p
rs1412364486 chr14:101065649    A/G
rs1458812624 chr14:101065658    C/A

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-369-3p
Exosome Serum     18589210
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-369-3p
Gemcitabine 60750 Drug interaction    RC00004121
D-Glucose 5793 Drug interaction    RC00004119
Doxorubicin 31703 Drug interaction    RC00004120
Verapamil 2520 Drug interaction    RC00004118
Mistletoe lectin-I - Drug interaction    RC00004122
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-369-3p
Cisplatin 5702198       28511796

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-369-3p
Interactor2: ORF8

Evidence Support:


Prediction-Evidence miRBase
Support Database ViRBase

References:


PMID 32547891 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Among 2,654 mature entries of Homo sapiens in miRBase Release 22.1, 479 of them could target SARS-CoV-2 genes (Supplemental Files-human to virus). While Envelope and ORF6 genes were targeted by single miRNAs, ORF1ab appeared to be the target of 369 different human mature miRNAs (Table 2).

Starting a new search, please wait ...