Detail Information

Basic Information:


  VIRBase ID:  

HVID00008726

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-520e-5p ORF1ab
miRBase
Accession/Entrez ID		 MIMAT0037324 1489680
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sarsp1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-520e-5p
rs1240425558 chr19:53675746    T/A
rs1240425558 chr19:53675746    T/G
rs1264548432 chr19:53675734    G/A
rs1405457733 chr19:53675726    C/G
rs1416448161 chr19:53675739    C/A
rs1440647938 chr19:53675747    G/A
rs536531741 chr19:53675736    A/C
rs751958312 chr19:53675740    A/C

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-520e-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Brain tissue     23382797

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-520e-5p
Interactor2: ORF1ab

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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