Detail Information

Basic Information:


  VIRBase ID:  

HVID00008703

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-8085 ORF1ab
miRBase
Accession/Entrez ID		 MIMAT0031012 1489680
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sarsp1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-8085
rs1013047154 chr19:44758675    A/G
rs1186475502 chr19:44758678    A/T
rs1271801278 chr19:44758683    G/A
rs141410012 chr19:44758687    C/T
rs1002731351 chr19:44758667    TG/T
rs1212461501 chr19:44758672    G/A
rs1369067068 chr19:44758669    G/A
rs746875246 chr19:44758668    G/A
rs746875246 chr19:44758668    G/T
rs768189924 chr19:44758674    G/A
rs894258580 chr19:44758673    A/G

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-8085
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-8085
Interactor2: ORF1ab

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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