Detail Information

Basic Information:


  VIRBase ID:  

HVID00008574

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6889-5p sars9b
miRBase
Accession/Entrez ID		 MIMAT0027678 1489679
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sars9b

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6889-5p
rs749955549 chr22:41253031    C/T
rs764701031 chr22:41253028    G/A
rs764701031 chr22:41253028    G/C
rs770038443 chr22:41253027    C/T
rs887125506 chr22:41253030    A/T
rs991058489 chr22:41253045    A/C
rs1226659948 chr22:41253040    C/A
rs146254801 chr22:41253043    C/A
rs146254801 chr22:41253043    C/T
rs568096458 chr22:41253042    C/G
rs568096458 chr22:41253042    C/T
rs767912775 chr22:41253044    G/A

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6889-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6889-5p
Interactor2: sars9b

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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