Detail Information

Basic Information:


  VIRBase ID:  

HVID00008468

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6850-5p sars9b
miRBase
Accession/Entrez ID
MIMAT0027600 1489679
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sars9b

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6850-5p
rs1164773569 chr8:144791973    C/A
rs1358686016 chr8:144791972    C/A
rs1362812096 chr8:144791978    C/T
rs1460308623 chr8:144791971    GC/G
rs200039333 chr8:144791975    C/T
rs370097454 chr8:144791983    G/A
rs370097454 chr8:144791983    G/T
rs375814230 chr8:144791981    G/C
rs748367262 chr8:144791970    C/A
rs748367262 chr8:144791970    C/T
rs772288137 chr8:144791976    G/A
rs772288137 chr8:144791976    G/C
rs111376131 chr8:144791989    C/G
rs111376131 chr8:144791989    C/T
rs111710483 chr8:144791990    A/T
rs1160376103 chr8:144791984    T/C
rs1400058311 chr8:144791987    C/T
rs1423245225 chr8:144791986    C/T
rs777346795 chr8:144791988    G/A

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6850-5p
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6850-5p
Interactor2: sars9b

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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