Detail Information

Basic Information:


  VIRBase ID:  

HVID00008383

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6821-5p sars9b
miRBase
Accession/Entrez ID		 MIMAT0027542 1489679
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sars9b

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6821-5p
rs145509761 chr22:49962881    A/C
rs200639371 chr22:49962876    G/A
rs547561980 chr22:49962880    G/A
rs547561980 chr22:49962880    G/C
rs752489243 chr22:49962874    T/TCCAC
rs760508730 chr22:49962879    C/G
rs760508730 chr22:49962879    C/T
rs761757255 chr22:49962885    G/C
rs765096620 chr22:49962888    G/A
rs926809294 chr22:49962884    C/T
rs376408360 chr22:49962870    G/A
rs376408360 chr22:49962870    G/C
rs749323042 chr22:49962869    C/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6821-5p
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6821-5p
Interactor2: sars9b

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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