Detail

Detail Information

Basic Information:

VIRBase ID:

HVID00008094

Virus:

SARS coronavirus Tor2

Host:

Homo sapiens

Confidence Score:

0.2381

Interaction Type:

Host-Virus interaction

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-655-5p	N
miRBase Accession/Entrez ID	MIMAT0026626	1489678
Organism	Homo sapiens	SARS coronavirus Tor2
Category	miRNA	mRNA
Alias	-	sars9a

ncRNA SNP information:

Resource

Symbol

SNP ID

SNP Position

Ref/Alt

miRNASNP-v3

hsa-miR-655-5p

rs369862924	chr14:101049582	C/T
rs373094888	chr14:101049589	T/C
rs552601004	chr14:101049583	G/A
rs569206109	chr14:101049586	T/C
rs753191773	chr14:101049585	G/A
rs757713353	chr14:101049581	C/T
rs778280798	chr14:101049593	C/T
rs754023562	chr14:101049576	G/A
rs754023562	chr14:101049576	G/T
rs766575622	chr14:101049575	G/A

RNA Localization:

Resource

Symbol

Subcellular Localization

Tissue or Cell Line

PMID

RNALocate

hsa-miR-655-5p

Exosome	Plasma	23663360
Exosome	Breast milk\|Cell lines\|Epididymal epithelial cells\|Osteoblast\|Plasma\|Primary glioblastoma neurosphere cells\|Primary keratinocyte\|Saliva\|Serum\|Urine	-
Microvesicle	Cell lines(GBM46\|GBM8\|HaCaT\|K562\|MCF-10A\|MCF-7\|MGG75)\|Plasma\|Primary glioblastoma neurosphere cells\|Primary keratinocytes	-

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-655-5p

Interactor2: N

Evidence Support:

Prediction-Evidence	IntaRNA//miRanda//psRNATarget
Support Database	ViRBase

References:

PMID	32765592	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	From our rigorous analysis pipeline, which covers three different well-established algorithms (IntaRNA, miRanda, and psRNATarget) to predict RNA-RNA interactions, we have identified 122 and 106 host antiviral miRNAs against SARS-CoV (R) and SARS-CoV-2 (R), respectively (Figures 2A,B, Supplementary File 2).

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