Detail Information

Basic Information:


  VIRBase ID:  

HVID00008065

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-134-3p sars9b
miRBase
Accession/Entrez ID		 MIMAT0026481 1489679
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sars9b

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-134-3p
rs1212462908 chr14:101054745    T/C
rs1278249300 chr14:101054741    C/CA
rs1415917765 chr14:101054740    C/T
rs752580711 chr14:101054749    C/T
rs752786233 chr14:101054754    A/G
rs752786233 chr14:101054754    A/T
rs765201848 chr14:101054742    A/C
rs760717795 chr14:101054739    G/A
rs773121278 chr14:101054738    G/A

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-134-3p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Myotube     27396686
Mitochondrion Skeletal muscle myoblasts     21637849

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-134-3p
Interactor2: sars9b

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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