Detail Information

Basic Information:


  VIRBase ID:  

HVID00007727

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-4758-3p sars9b
miRBase
Accession/Entrez ID		 MIMAT0019904 1489679
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sars9b

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-4758-3p
rs1162390284 chr20:62332492    G/C
rs1326074553 chr20:62332494    G/A
rs1353228989 chr20:62332499    C/G
rs1406510380 chr20:62332493    G/A
rs748944898 chr20:62332500    A/T
rs755642414 chr20:62332490    G/A
rs756946016 chr20:62332501    G/A
rs777364627 chr20:62332498    T/A
rs777364627 chr20:62332498    T/G
rs778827403 chr20:62332502    C/T
rs1312340329 chr20:62332507    G/A
rs376998428 chr20:62332508    G/C
rs745792139 chr20:62332505    G/A
rs776833678 chr20:62332511    C/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-4758-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-4758-3p
Interactor2: sars9b

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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