Detail Information

Basic Information:


  VIRBase ID:  

HVID00006862

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320b N
miRBase
Accession/Entrez ID		 MIMAT0005792 1489678
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sars9a

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320b
rs1156276707 chr1:116671796    G/T
rs1311857670 chr1:116671805    GCAAA/G
rs1373244526 chr1:116671806    C/T
rs1434535374 chr1:116671803    G/C
rs755613466 chr1:116671797    T/C
rs779451916 chr1:116671801    G/C
rs1303311077 chr1:224257059    A/T
rs1313950455 chr1:224257062    C/A
rs1333032274 chr1:224257051    G/T
rs1445839645 chr1:224257055    T/C
rs1465806287 chr1:224257050    TGCCC/T
rs745315768 chr1:224257052    C/T
rs769446888 chr1:224257054    C/T
rs1189118293 chr1:116671788    A/G
rs1199375375 chr1:116671794    G/A
rs1411861918 chr1:116671791    G/T
rs1469116635 chr1:116671792    C/CTGGGTTGAGAGGGCAAACAAATTAACTAAT
rs1030808536 chr1:224257064    A/T
rs774951709 chr1:224257069    T/C

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320b
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Pooled sera     27278097
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Ovarian follicular fluid     22116803
Exosome Plasma     23663360
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Nasopharyngeal carcinoma cells     20498841

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-320b
Eloxatine 5310940 Drug interaction    RC00007663
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007662
Benzene 241 Drug interaction    RC00007661
Marine fungal metabolite 1386A - Drug interaction    RC00007664
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-320b
Topotecan       60700

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320b
Interactor2: N

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

Starting a new search, please wait ...