Detail Information

Basic Information:


  VIRBase ID:  

HVID00006796

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-665 ORF1ab
miRBase
Accession/Entrez ID		 MIMAT0004952 1489680
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sarsp1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-665
rs1161003917 chr14:100875086    G/A
rs1203257535 chr14:100875094    T/C
rs1251413334 chr14:100875092    C/T
rs1321122076 chr14:100875089    G/T
rs1374122857 chr14:100875088    G/A
rs759481457 chr14:100875093    C/G
rs1201625296 chr14:100875078    A/G
rs1490584325 chr14:100875079    G/C
rs747741348 chr14:100875077    C/G
rs747741348 chr14:100875077    C/T

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-665
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome K562 cells     24460325
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Mesenchymal stem cells|Urine     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-665
Interactor2: ORF1ab

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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