Detail Information

Basic Information:


  VIRBase ID:  

HVID00006728

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-330-5p ORF1ab
miRBase
Accession/Entrez ID		 MIMAT0004693 1489680
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - sarsp1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-330-5p
rs1349824380 chr19:45639070    A/G
rs1359949384 chr19:45639062    G/A
rs760888385 chr19:45639051    C/G
rs761051145 chr19:45639055    GAC/G
rs1450351295 chr19:45639066    A/T
rs562108564 chr19:45639069    G/T
rs768769902 chr19:45639068    A/G

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-330-5p
Exosome HCC tissues     30542726
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-330-5p
D-Glucose 5793 Drug interaction    RC00007082
Mistletoe lectin-I - Drug interaction    RC00007083
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-330-5p
Etoposide 36462       23028896

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-330-5p
Interactor2: ORF1ab

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

Starting a new search, please wait ...