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Detail Information
Basic Information:
VIRBase ID:
HVID00006704
Virus:
SARS coronavirus Tor2
Host:
Homo sapiens
Confidence Score:
0.1828
Interaction Type:
Host-Virus interaction
Interactor Information:
Interactor1
Interactor2
Symbol
hsa-miR-200c-5p
ORF1ab
miRBase
Accession/Entrez ID
MIMAT0004657
1489680
Organism
Homo sapiens
SARS coronavirus Tor2
Category
miRNA
mRNA
Alias
-
sarsp1
ncRNA SNP information:
Resource
Symbol
SNP ID
SNP Position
Ref/Alt
miRNASNP-v3
hsa-miR-200c-5p
rs1220589670
chr12:6963703
C/T
rs1277597787
chr12:6963716
A/C
rs372372905
chr12:6963719
G/A
rs942672545
chr12:6963713
A/G
rs1318673559
chr12:6963704
G/A
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
hsa-miR-200c-5p
Exosome
Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine
-
Microvesicle
Seminal plasma
23539611
Microvesicle
Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes
-
Interaction Network
(The top 100 interactions)
:
Interactor1: hsa-miR-200c-5p
Interactor2: ORF1ab
Evidence Support:
Prediction-Evidence
miRTarP
Support Database
ViRBase
References:
PMID
33173539
Target region
None
Source
ViRBase
Interactor1 expression
None
Tissue or cell line
None
Interactor2 expression
None
Description
Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).
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