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Detail Information
Basic Information:
VIRBase ID:
HVID00006644
Virus:
SARS coronavirus Tor2
Host:
Homo sapiens
Confidence Score:
0.1828
Interaction Type:
Host-Virus interaction
Interactor Information:
Interactor1
Interactor2
Symbol
hsa-miR-99a-3p
ORF1ab
miRBase
Accession/Entrez ID
MIMAT0004511
1489680
Organism
Homo sapiens
SARS coronavirus Tor2
Category
miRNA
mRNA
Alias
-
sarsp1
ncRNA SNP information:
Resource
Symbol
SNP ID
SNP Position
Ref/Alt
miRNASNP-v3
hsa-miR-99a-3p
rs1214222916
chr21:16539147
T/C
rs1419616925
chr21:16539158
T/A
rs763134262
chr21:16539151
A/G
rs766428664
chr21:16539153
G/A
rs774748688
chr21:16539159
G/C
rs950382507
chr21:16539154
G/A
rs1271070422
chr21:16539142
C/T
rs913397001
chr21:16539145
G/A
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
hsa-miR-99a-3p
Exosome
Plasma
23663360
Exosome
Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine
-
Microvesicle
Fibroblasts|Mesenchymal stem cells
-
Mitochondrion
Skeletal muscle myoblasts
21637849
Interaction Network
(The top 100 interactions)
:
Interactor1: hsa-miR-99a-3p
Interactor2: ORF1ab
Evidence Support:
Prediction-Evidence
miRTarP
Support Database
ViRBase
References:
PMID
33173539
Target region
None
Source
ViRBase
Interactor1 expression
None
Tissue or cell line
None
Interactor2 expression
None
Description
Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).
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