Detail Information

Basic Information:


  VIRBase ID:  

HVID00006525

  Virus:  

SARS coronavirus Tor2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-608 S
miRBase
Accession/Entrez ID		 MIMAT0003276 1489668
Organism Homo sapiens SARS coronavirus Tor2
Category miRNA mRNA
Alias - E2//sars2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-608
rs1353373743 chr10:100974999    CA/C
rs368610511 chr10:100975023    G/A
rs4919510 chr10:100975021    C/G
rs558234881 chr10:100975014    G/T
rs757887469 chr10:100975010    T/C
rs770502722 chr10:100975022    C/T
rs1313026429 chr10:100975002    G/C
rs1397346443 chr10:100975003    G/C
rs749799472 chr10:100975006    G/A
rs958002673 chr10:100975007    G/C

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-608
Exosome Primary ovarian tumor cells|Serum     18589210
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-608
Diethylstilbestrol 448537 Drug interaction    RC00006118
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00006117
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-608
Pha-665752       10461815

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-608
Interactor2: S

Evidence Support:


Prediction-Evidence miRTarP
Support Database ViRBase

References:


PMID 33173539 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Interestingly, we observed that 717 miRNAs targeting SARS-CoV-2 genes are common with those targeting SARS-CoV genes, possibly due to high genome similarity (Xu et al., 2020; Zhang and Holmes, 2020, p. 2) (Supplementary Table S7).

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