Detail Information

Basic Information:


  VIRBase ID:  

HVID00000043

  Virus:  

Borna disease virus 1 (BoDV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.8808

  Interaction Type:  

Host-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-146a-3p P40
miRBase
Accession/Entrez ID		 MIMAT0004608 P40
Organism Homo sapiens Borna disease virus 1 (BoDV-1)
Category miRNA protein
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-146a-3p
rs1323710653 chr5:160485408    C/T
rs1343966428 chr5:160485421    G/C
rs529455292 chr5:160485429    G/T
rs772931224 chr5:160485420    A/G
rs1173033188 chr5:160485411    CT/C
rs1234876154 chr5:160485413    G/GA
rs2910164 chr5:160485411    C/G

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-146a-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-146a-3p
Interactor2: P40

Evidence Support:


Strong-Evidence RT-qPCR//Western blot
Support Database ViRBase

References:


PMID 31330207 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line HMC3 cells Interactor2 expression None
Description We also examined the effect of miR-146a on viral protein expression; induction of BoDV-1 P40 protein expression in miR-146a-overexpressing HME3 cells was found compared with the level in the control (Fig. 2C, D).

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