Basic Information:

  VIRBase ID:  

HHID00109448

  Virus:  

Severe acute respiratory syndrome-related coronavirus (SARS)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-92b-3p:  MIMAT0003218          SMAD3:  NM_005902     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-92b-3p	SMAD3
miRBase Accession/Entrez ID	MIMAT0003218	4088
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	HSPC193//HsT17436//JV15-2//LDS1C//LDS3//MADH3

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-92b-3p	rs1235528450 chr1:155195237    T/C rs12759620 chr1:155195253    G/C rs1350664926 chr1:155195246    C/T rs1355214420 chr1:155195256    T/TCCGGCCCCC

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SMAD3	chr15:67452930(+) A-I      intronic chr15:67452962(+) A-I      intronic chr15:67358882(+) A-I      intronic chr15:67451670(+) A-I      intronic chr15:67451671(+) A-I      intronic chr15:67452947(+) A-I      intronic chr15:67394254(+) A-I      intronic chr15:67451683(+) A-I      intronic chr15:67451672(+) A-I      intronic chr15:67452950(+) A-I      intronic chr15:67394253(+) A-I      intronic chr15:67362173(+) A-I      intronic chr15:67403460(+) A-I      intronic chr15:67451592(+) A-I      intronic chr15:67451581(+) A-I      intronic chr15:67451570(+) A-I      intronic chr15:67416609(+) A-I      intronic chr15:67416603(+) A-I      intronic chr15:67416411(+) A-I      intronic chr15:67416365(+) A-I      intronic chr15:67416349(+) A-I      intronic chr15:67415758(+) A-I      intronic chr15:67389768(+) A-I      intronic chr15:67389769(+) A-I      intronic chr15:67415506(+) A-I      intronic chr15:67415445(+) A-I      intronic chr15:67415389(+) A-I      intronic chr15:67367127(+) A-I      intronic chr15:67452943(+) A-I      intronic chr15:67456585(+) A-I      intronic chr15:67412396(+) A-I      intronic chr15:67456466(+) A-I      intronic chr15:67389771(+) A-I      intronic chr15:67368181(+) A-I      intronic chr15:67456616(+) A-I      intronic chr15:67456372(+) A-I      intronic chr15:67412356(+) A-I      intronic chr15:67456581(+) A-I      intronic chr15:67405627(+) A-I      intronic chr15:67366170(+) A-I      intronic chr15:67456546(+) A-I      intronic chr15:67392319(+) A-I      intronic chr15:67412179(+) A-I      intronic chr15:67456542(+) A-I      intronic chr15:67456516(+) A-I      intronic chr15:67456471(+) A-I      intronic chr15:67456470(+) A-I      intronic chr15:67368088(+) A-I      intronic chr15:67366112(+) A-I      intronic chr15:67389693(+) A-I      intronic chr15:67367131(+) A-I      intronic chr15:67367102(+) A-I      intronic chr15:67367157(+) A-I      intronic chr15:67455501(+) A-I      intronic chr15:67366211(+) A-I      intronic chr15:67366195(+) A-I      intronic chr15:67366149(+) A-I      intronic chr15:67366142(+) A-I      intronic chr15:67366113(+) A-I      intronic chr15:67410310(+) A-I      intronic chr15:67455495(+) A-I      intronic chr15:67368114(+) A-I      intronic chr15:67455405(+) A-I      intronic chr15:67455376(+) A-I      intronic chr15:67453054(+) A-I      intronic chr15:67412228(+) A-I      intronic chr15:67453053(+) A-I      intronic chr15:67453034(+) A-I      intronic chr15:67453018(+) A-I      intronic chr15:67415675(+) A-I      intronic chr15:67368202(+) A-I      intronic chr15:67366106(+) A-I      intronic chr15:67366069(+) A-I      intronic chr15:67366061(+) A-I      intronic chr15:67453015(+) A-I      intronic chr15:67415386(+) A-I      intronic chr15:67453011(+) A-I      intronic chr15:67452994(+) A-I      intronic chr15:67452958(+) A-I      intronic chr15:67452927(+) A-I      intronic chr15:67452894(+) A-I      intronic chr15:67452891(+) A-I      intronic chr15:67452855(+) A-I      intronic chr15:67452839(+) A-I      intronic chr15:67415717(+) A-I      intronic chr15:67451509(+) A-I      intronic chr15:67451652(+) A-I      intronic chr15:67451609(+) A-I      intronic chr15:67451606(+) A-I      intronic chr15:67456143(+) A-I      intronic chr15:67410283(+) A-I      intronic chr15:67412332(+) A-I      intronic chr15:67451478(+) A-I      intronic chr15:67412397(+) A-I      intronic chr15:67367047(+) A-I      intronic chr15:67368106(+) A-I      intronic chr15:67363921(+) A-I      intronic chr15:67455555(+) A-I      intronic chr15:67416500(+) A-I      intronic chr15:67455512(+) A-I      intronic chr15:67367189(+) A-I      intronic chr15:67415375(+) A-I      intronic chr15:67415739(+) A-I      intronic chr15:67415579(+) A-I      intronic chr15:67443457(+) A-I      intronic chr15:67415685(+) A-I      intronic chr15:67368133(+) A-I      intronic chr15:67368119(+) A-I      intronic chr15:67452882(+) A-I      intronic chr15:67368174(+) A-I      intronic chr15:67367193(+) A-I      intronic chr15:67416427(+) A-I      intronic chr15:67366220(+) A-I      intronic chr15:67416492(+) A-I      intronic chr15:67362144(+) A-I      intronic chr15:67367097(+) A-I      intronic chr15:67476581(+) A-I      intronic chr15:67368185(+) A-I      intronic chr15:67415373(+) A-I      intronic chr15:67415687(+) A-I      intronic chr15:67410410(+) A-I      intronic chr15:67362114(+) A-I      intronic chr15:67421012(+) A-I      intronic chr15:67410364(+) A-I      intronic chr15:67455333(+) A-I      intronic chr15:67368100(+) A-I      intronic chr15:67416601(+) A-I      intronic chr15:67410351(+) A-I      intronic chr15:67452978(+) A-I      intronic chr15:67415787(+) A-I      intronic chr15:67405710(+) A-I      intronic chr15:67455441(+) A-I      intronic chr15:67366158(+) A-I      intronic chr15:67368198(+) A-I      intronic chr15:67455332(+) A-I      intronic chr15:67368203(+) A-I      intronic chr15:67363962(+) A-I      intronic chr15:67415671(+) A-I      intronic chr15:67415676(+) A-I      intronic chr15:67405711(+) A-I      intronic chr15:67405702(+) A-I      intronic chr15:67368210(+) A-I      intronic chr15:67416395(+) A-I      intronic chr15:67416561(+) A-I      intronic chr15:67415408(+) A-I      intronic chr15:67415680(+) A-I      intronic chr15:67368146(+) A-I      intronic chr15:67410342(+) A-I      intronic chr15:67416562(+) A-I      intronic chr15:67456395(+) A-I      intronic chr15:67362119(+) A-I      intronic chr15:67478497(+) A-I      intronic chr15:67368044(+) A-I      intronic chr15:67452949(+) A-I      intronic chr15:67363875(+) A-I      intronic chr15:67483483(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SMAD3	chr15:67368146(+) A-G intron -    22484847 chr15:67415675(+) A-G intron -    22484847 chr15:67451478(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SMAD3	chr15:67356224-67356225(+) m6A 5'UTR       24981863 chr15:67356275-67356276(+) m6A 5'UTR       24981863 chr15:67358549-67358550(+) m1A CDS//intron       26863196//26863410 chr15:67358614-67358615(+) m6A CDS//intron       24284625//24981863//26404942 chr15:67390932-67390933(+) m6A 5'UTR//intron       24284625 chr15:67418223-67418224(+) m6A 5'UTR//intron       24981863 chr15:67457312-67457313(+) m6A 5'UTR//CDS//exon       24284625 chr15:67457419-67457420(+) m6A CDS//exon       24284625//24981863 chr15:67457677-67457678(+) m6A CDS//exon       24284625//24981863 chr15:67459093-67459094(+) m6A 5'UTR//intron       24284625//24981863 chr15:67459118-67459119(+) m6A 5'UTR//CDS//exon       24284625//24981863 chr15:67459154-67459155(+) m6A 5'UTR//CDS//exon       24284625//24981863//26404942 chr15:67459173-67459174(+) m6A CDS//exon       24284625//24981863//26404942 chr15:67462900-67462901(+) m6A CDS//exon       24284625//24981863//26404942 chr15:67462971-67462972(+) m6A exon//intron       24284625//24981863 chr15:67466703-67466704(+) m6A exon//intron       24284625 chr15:67466805-67466806(+) m6A exon//intron       24284625 chr15:67473784-67473785(+) Cm CDS//intron       - chr15:67482753-67482754(+) m6A CDS//exon//intron       24284625//24209618//24981863 chr15:67482876-67482877(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//26404942//27773535//22608085 chr15:67482943-67482944(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:67483023-67483024(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:67483035-67483036(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:67483056-67483057(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:67483073-67483074(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483144-67483145(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483180-67483181(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483229-67483230(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483246-67483247(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483310-67483311(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483358-67483359(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483405-67483406(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483430-67483431(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483480-67483481(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483512-67483513(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483525-67483526(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483562-67483563(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67483916-67483917(+) m6A 3'UTR//intron       24284625//24981863 chr15:67483927-67483928(+) m6A 3'UTR//intron       24284625//24981863 chr15:67484050-67484051(+) m6A 3'UTR//intron       26404942 chr15:67484252-67484253(+) m6A 3'UTR//intron       24209618//24981863//26404942 chr15:67484320-67484321(+) m6A 3'UTR//intron       24209618//24981863//26404942 chr15:67484329-67484330(+) m6A 3'UTR//intron       24981863//26404942 chr15:67484334-67484335(+) m6A 3'UTR//intron       24981863//26404942 chr15:67484616-67484617(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr15:67484642-67484643(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67484675-67484676(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67484712-67484713(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67484720-67484721(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67484730-67484731(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67484830-67484831(+) m6A 3'UTR//intron       24284625//24209618//24981863//26404942//22575960//22608085 chr15:67484870-67484871(+) m6A 3'UTR//intron       24284625//24209618 chr15:67484878-67484879(+) m6A 3'UTR//intron       24284625//24209618 chr15:67485027-67485028(+) m6A 3'UTR//intron       24981863 chr15:67485134-67485135(+) m6A 3'UTR//intron       24981863//26404942 chr15:67485187-67485188(+) m6A 3'UTR//intron       24981863//26404942 chr15:67485202-67485203(+) m6A 3'UTR//intron       24981863//26404942 chr15:67485289-67485290(+) m6A 3'UTR//exon       26404942 chr15:67485323-67485324(+) m6A 3'UTR//exon       26404942 chr15:67485510-67485511(+) m6A 3'UTR//exon       26404942 chr15:67485525-67485526(+) m6A 3'UTR       26404942 chr15:67485548-67485549(+) m6A 3'UTR       26404942 chr15:67485684-67485685(+) m6A 3'UTR       24981863 chr15:67485711-67485712(+) m6A 3'UTR       24981863 chr15:67485871-67485872(+) m6A 3'UTR       24284625 chr15:67485909-67485910(+) m6A 3'UTR       24284625 chr15:67485924-67485925(+) m6A 3'UTR       24284625 chr15:67485951-67485952(+) m6A 3'UTR       24284625 chr15:67486071-67486072(+) m6A 3'UTR       26404942 chr15:67486164-67486165(+) m6A 3'UTR       26404942 chr15:67486385-67486386(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22575960//22608085 chr15:67486439-67486440(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22575960//22608085 chr15:67486513-67486514(+) m6A 3'UTR       24284625//24981863//26404942 chr15:67486518-67486519(+) m6A 3'UTR       24284625//24981863//26404942 chr15:67486677-67486678(+) m6A 3'UTR       24209618//24981863//26404942//22608085 chr15:67486744-67486745(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr15:67486762-67486763(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr15:67486784-67486785(+) m6A 3'UTR       24209618//24981863//26404942//22608085 chr15:67486799-67486800(+) m6A 3'UTR       24209618//24981863//26404942//22608085 chr15:67486908-67486909(+) m6A 3'UTR       24284625//24981863//26404942 chr15:67486917-67486918(+) m6A 3'UTR       24284625//24981863//26404942 chr15:67486972-67486973(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22608085 chr15:67487053-67487054(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:67487060-67487061(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:67487074-67487075(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:67487094-67487095(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67487142-67487143(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:67487253-67487254(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr15:67487285-67487286(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-92b-3p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Peripheral blood     31746410 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Cerebrospinal fluid     25420022 Exosome Blood|B lymphoblastoid cells|Breast tissue|Endothelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Seminal plasma     23539611 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	SMAD3	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-92b-3p	Iodine Green 9956454 Drug sensitive Sensorad 99342 Drug sensitive 8-Aminoadenosine 96851 Drug resistant Gardenin B 96539 Drug sensitive Hydrazinecarboximidamide, 2,2'-(carbonylbis(imino-3,1-phenyleneethylidyne))bis-, hydrochloride 9577144 Drug sensitive Actinomycin X4357G methoxime 9573583 Drug sensitive (3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive L-2-Aminobutyric acid 80283 Drug sensitive Vancide 26 79411 Drug sensitive Cinerubin B 73593 Drug sensitive 4-(2-Naphthylamino)phenol 7141 Drug sensitive Sulbentine 67686 Drug sensitive Ixabepilone 6445540 Drug sensitive Piriqualone 6015423 Drug sensitive trans-1,2-Bis(propylsulfonyl)ethylene 5904452 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive Artelasticin 5471311 Drug sensitive 2-(1,3-Benzodioxol-5-yl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one 5466137 Drug sensitive 6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive Herveline O 5459269 Drug sensitive Cuspidatin C 5459164 Drug sensitive Thiram 5455 Drug sensitive (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Indanthren Corinth RK 5351878 Drug sensitive 5-Phenyl-N-(3,4,5-trimethoxyphenyl)-1,3-oxazol-2-amine 5329854 Drug sensitive 1-[3-(Propylamino)phenyl]-N-(pyridin-4-ylmethylideneamino)pyrazolo[3,4-d]pyrimidin-4-amine 53239979 Drug sensitive Vorinostat 5311 Drug sensitive Spiperone 5265 Drug resistant Kekule 499328 Drug sensitive 10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive 6-Methoxy-7-(2lambda(5)-1,2-triazadienyl)-5,8-quinolinedione 494043 Drug sensitive Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive BAS100 Monohydrate 45028404 Drug sensitive 1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive Isopinnatal 44558939 Drug sensitive 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive 2,6-Epoxy-2H-1-benzoxocin-5(6H)-one, 6,8-dimethyl- 434882 Drug sensitive Di-n-octyl-secalonsaure A 430141 Drug sensitive 2-Amino-4-(2-hydroxy-4-methylphenyl)-5-phenylpyrimidine 392744 Drug sensitive beta-Lapachone 3885 Drug sensitive Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive 4-Phenacyloxychromen-2-one 386272 Drug resistant 2-Ethylaminoestradiol 384235 Drug sensitive (-)7,8-Dihydrocalanolide A 383107 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 4-Methylthio-N-(3,4,5-trimethoxybenzyl)aniline 373808 Drug sensitive Sanguilutine pseudobase 371258 Drug sensitive 1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive 1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive Maxima isoflavone D 343081 Drug sensitive Bis(helenalinyl)glutarate 336831 Drug sensitive Rustaiyan A 324967 Drug sensitive (15S)-15-Ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one 2724040 Drug sensitive Antineoplastic-92915 261051 Drug sensitive 5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive Prumycin HCl 24197905 Drug resistant 9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive 4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive 3-Amino-N-(2-fluorophenyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide 1856915 Drug sensitive Sudan II 18386 Drug sensitive (2R)-2-[(3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(5S)-5-[(3S)-5-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoic acid 152743331 Drug sensitive Arsenic trioxide 14888 Drug sensitive Astrazon Orange R 135747272 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive (2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive Melampodinin 11953936 Drug sensitive 2,2'-Bioxirane 11254 Drug sensitive Perillyl alcohol 10819 Drug sensitive Cladospirone bisepoxide 10316810 Drug sensitive Chimaphilin 101211 Drug sensitive 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant 1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant tgf.alpha.-pe40 - Drug resistant tp4ek - Drug resistant tunicamycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive (z) 4-acetoxy-(3,4',5)-trimethoxystilbene - Drug sensitive (Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive 1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive 2-(4-(methylsulfonyl)phenyl)-6-p-tolyl-4,5-dihydropyridazin-3(2H)-one - Drug sensitive 2,4-diethoxyestra-1,3,5(10)trien-3,17.beta.-diol - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 4-thiomorpholinecarbodithioic acid, antimony complex - Drug sensitive 5-[2-(4-methoxyphenyl)ethyl]-1,2,3-dimethoxy benzene - Drug sensitive 7-n,n-dimethylamino brefeldin a hydrochloride - Drug sensitive 9-acridinamine, n-(4-ethoxyphenyl)-, monohydrochloride - Drug sensitive anthracen-9-one, 10-[(2-methoxyphenyl)methylene]- - Drug sensitive benzamide, 5-bromo-2-hydroxy-n-[3-(trifluoromethyl)phenyl]- - Drug sensitive benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive inosine, 6-thio-, 2',3',5'-tris(4-methoxybenzoate) - Drug sensitive isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive phosphonium, (3-bromopropyl)triphenyl- bromide - Drug sensitive (Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive 2-amino-5-chloro-6-(2-thiazolyloxy)-benzimidazole - Drug sensitive 4-carbo-1-thiazolidine-3-o-gluconyl-.gamma.-lactone - Drug sensitive 9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive antineoplastic-615538 - Drug sensitive antineoplastic-d665837 - Drug sensitive arylmethylene-f - Drug sensitive carzinostatin - Drug sensitive cyclo [n-naphthoyl-d-lys-asn-gln-trp-ala-val-d-ala-his-leu] - Drug sensitive geldanamycin-11-hexadecanic acid ester - Drug sensitive his 47-methyl ct - Drug sensitive n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-92b-3p	(S)-N-[1-(3-Morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide 9949648 Drug interaction    RC00005944 Gemcitabine 60750 Drug interaction    RC00005940 Vincristine 5978 Drug interaction    RC00005938 Eloxatine 5310940 Drug interaction    RC00005943 Diethylstilbestrol 448537 Drug interaction    RC00005942 Bortezomib 387447 Drug interaction    RC00005941 5-Fluorouracil 3385 Drug interaction    RC00005937 Doxorubicin 31703 Drug interaction    RC00005939 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005936 Trastuzumab - Drug interaction    RC00005945

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-92b-3p	Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-92b-3p
Interactor2: SMAD3

Evidence Support:

Prediction-Evidence	miRTarBase//miRWalk
Support Database	ViRBase

References:

PMID	33475497	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	Our data revealed that 709 miRNAs target these mRNAs, among which 145 functional MTIs were found and were subsequently selected as the most important interactions for further examination.